Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 7/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286214 | 0.98 | LPAR3 (0.45) | TYMSGRM4LMNACYP3A4NFKB1 | |
| SCHEMBL1285912 | 0.93 | TYMS (0.48) | TYMSGRM4LMNACYP3A4NFKB1 | |
| Water SCHEMBL9900532 | 0.91 | TYMS (0.46) | TYMSGRM4LMNACYP3A4NFKB1 | |
| SCHEMBL1285893 | 0.84 | GRM4 (0.56) | TYMSGRM4LMNACYP3A4NFKB1 | |
| SCHEMBL4413844 | 0.77 | TYMS (0.44) | TYMSGRM4LMNACYP3A4NFKB1 | |
| SCHEMBL2319390 | 0.75 | GGPS1 (0.58) | TYMSGRM4LMNACYP3A4NFKB1 | |
| SCHEMBL4413277 | 0.75 | TYMS (0.52) | TYMSGRM4LMNACYP3A4NFKB1 | |
| SCHEMBL19212014 | 0.73 | GGPS1 (0.56) | TYMSGRM4LMNACYP3A4NFKB1 | |
| SCHEMBL20699854 | 0.73 | LPAR3 (0.50) | TYMSGRM4LMNACYP3A4NFKB1 | |
| SCHEMBL1260815 | 0.73 | LPAR3 (0.50) | TYMSGRM4LMNACYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120089118-A1 | DELIVERY OF BISPHOSPHONATES BY MICROINJECTION SYSTEMS | A Nevada Corporation | 2012-04-12 | — | — | US | disclosed |
| WO-2012048285-A1 | DELIVERY OF BISPHOSPHONATES BY MICROINJECTION SYSTEMS | LANCO BIOSCIENCES, INC. (US) | 2012-04-12 | — | — | WO | disclosed |