Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 10/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285912 | 0.86 | TYMS (0.48) | GRM4ALDH1A1FDPSLMNAPDE3A | |
| Water SCHEMBL9900532 | 0.84 | TYMS (0.46) | GRM4ALDH1A1FDPSLMNAPDE3A | |
| SCHEMBL1285642 | 0.84 | TYMS (0.46) | GRM4ALDH1A1FDPSLMNAPDE3A | |
| SCHEMBL1286214 | 0.82 | LPAR3 (0.45) | GRM4FDPSLMNATYMSCYP3A4 | |
| SCHEMBL4106973 | 0.77 | FDPS (0.58) | GRM4ALDH1A1FDPSLMNAPDE3A | |
| SCHEMBL9620269 | 0.74 | FDPS (0.56) | GRM4FDPSLMNAPDE3AADRB3 | |
| SCHEMBL19211969 | 0.73 | GRM4 (0.52) | GRM4ALDH1A1FDPSLMNAPDE3A | |
| SCHEMBL5063485 | 0.72 | GRM4 (1.00) | GRM4ALDH1A1FDPSLMNATYMS | |
| SCHEMBL10976071 | 0.71 | GRM4 (0.52) | GRM4ALDH1A1FDPSLMNAPDE3A | |
| SCHEMBL11347918 | 0.70 | GRM4 (0.50) | GRM4ALDH1A1FDPSLMNAPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120089118-A1 | DELIVERY OF BISPHOSPHONATES BY MICROINJECTION SYSTEMS | A Nevada Corporation | 2012-04-12 | — | — | US | disclosed |
| WO-2012048285-A1 | DELIVERY OF BISPHOSPHONATES BY MICROINJECTION SYSTEMS | LANCO BIOSCIENCES, INC. (US) | 2012-04-12 | — | — | WO | disclosed |
| US-4621077-A | Pharmacologically active biphosphonates, process for the preparation thereof and pharmaceutical compositions therefrom | ISTITUTO GENTILI S.P.A. (IT) | 1986-11-04 | — | — | US | disclosed |