Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.55 |
| ▸ | CDK4 | P11802 | 2/20 | 0.55 |
| ▸ | CCND1 | P24385 | 2/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090159 | 0.86 | CDK4 (0.71) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL14452732 | 0.82 | CCNE2 (0.58) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL7148608 | 0.76 | CDK4 (0.66) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL18292498 | 0.75 | NPSR1 (0.54) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL4025529 | 0.74 | CCNE2 (0.83) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL4816704 | 0.74 | CDK4 (0.68) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL7146443 | 0.74 | CDK4 (0.68) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL7145484 | 0.74 | CDK4 (0.68) | CDK2CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL5231898 | 0.74 | KDM4E (0.62) | KDM4EALDH1A1NPC1HSD17B10GAA | |
| SCHEMBL6749016 | 0.73 | CDK4 (0.58) | CDK2CCNE2CDK4CCND1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364212-B1 | THREE HYBRID ASSAY SYSTEM | GPC BIOTECH AG (DE) | 2011-02-02 | — | — | EP | disclosed |
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | disclosed |