Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.51 |
| ▸ | RAF1 | P04049 | 7/20 | 0.44 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5776196 | 0.84 | RAF1 (0.64) | LRRK2RAF1PIK3C3MAPTPOLB | |
| SCHEMBL1395119 | 0.84 | LRRK2 (0.64) | LRRK2RAF1PIK3C3MAPTPOLB | |
| SCHEMBL5776199 | 0.84 | RAF1 (0.64) | LRRK2RAF1PIK3C3MAPTPOLB | |
| SCHEMBL1395120 | 0.84 | LRRK2 (0.64) | LRRK2RAF1PIK3C3MAPTPOLB | |
| SCHEMBL5774037 | 0.77 | RAF1 (0.62) | LRRK2RAF1PIK3C3MAPTEGFR | |
| SCHEMBL1395231 | 0.77 | LRRK2 (0.62) | LRRK2RAF1PIK3C3MAPTPOLB | |
| SCHEMBL5774040 | 0.77 | RAF1 (0.62) | LRRK2RAF1PIK3C3MAPTEGFR | |
| SCHEMBL1395230 | 0.77 | LRRK2 (0.62) | LRRK2RAF1PIK3C3MAPTPOLB | |
| SCHEMBL13838786 | 0.77 | RAF1 (0.65) | LRRK2RAF1MAPTPOLBHTT | |
| SCHEMBL7982266 | 0.74 | RAF1 (0.44) | LRRK2RAF1PIK3C3MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364212-B1 | THREE HYBRID ASSAY SYSTEM | GPC BIOTECH AG (DE) | 2011-02-02 | — | — | EP | disclosed |