Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 13/20 | 0.43 |
| ▸ | CA2 | P00918 | 13/20 | 0.43 |
| ▸ | CA9 | Q16790 | 9/20 | 0.43 |
| ▸ | CA12 | O43570 | 8/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12856489 | 0.86 | EIF2AK2 (0.49) | EIF2AK2CA1CA2CA9CA12 | |
| SCHEMBL14040777 | 0.81 | EIF2AK2 (0.45) | EIF2AK2CA1CA2CA9CA12 | |
| SCHEMBL5167566 | 0.80 | CA1 (0.47) | EIF2AK2CA1CA2CA9CA12 | |
| SCHEMBL5427801 | 0.80 | CA1 (0.47) | EIF2AK2CA1CA2CA9CA12 | |
| SCHEMBL5421135 | 0.78 | EIF2AK2 (0.46) | EIF2AK2CA1CA2CA9CA12 | |
| SCHEMBL5421128 | 0.78 | EIF2AK2 (0.46) | EIF2AK2CA1CA2CA9CA12 | |
| SCHEMBL5740387 | 0.78 | CES1 (0.38) | CA1CA2CA9KDM4ELMNA | |
| SCHEMBL14040841 | 0.77 | EIF2AK2 (0.46) | EIF2AK2CA1CA2CA9CA12 | |
| SCHEMBL5439438 | 0.76 | CA1 (0.67) | EIF2AK2CA1CA2CA9CA12 | |
| SCHEMBL5171527 | 0.76 | CA1 (0.67) | EIF2AK2CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364212-B1 | THREE HYBRID ASSAY SYSTEM | GPC BIOTECH AG (DE) | 2011-02-02 | — | — | EP | disclosed |