Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 5/20 | 0.51 |
| ▸ | CA1 | P00915 | 5/20 | 0.51 |
| ▸ | CA2 | P00918 | 5/20 | 0.51 |
| ▸ | CA9 | Q16790 | 5/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441999 | 0.82 | ALDH1A1 (0.62) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL11573760 | 0.80 | DPP4 (0.58) | KDM4ENPC1ALDH1A1RAB9AHDAC1 | |
| SCHEMBL28063081 | 0.80 | SMN1; SMN2 (0.63) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL6847632 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL13518280 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL1515809 | 0.79 | PLAU (0.73) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL7348869 | 0.79 | ALDH1A1 (0.61) | KDM4ENPC1ALDH1A1RAB9AHDAC1 | |
| SCHEMBL13563342 | 0.79 | MAPT (0.63) | KDM4EHPGDNPC1ALDH1A1RAB9A | |
| SCHEMBL14385076 | 0.78 | SMN1; SMN2 (0.66) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL9674448 | 0.78 | NPC1 (0.68) | NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364212-B1 | THREE HYBRID ASSAY SYSTEM | GPC BIOTECH AG (DE) | 2011-02-02 | — | — | EP | disclosed |