Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21088308 | 0.80 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL30836864 | 0.78 | SIGMAR1 (0.37) | SIGMAR1 | |
| SCHEMBL2560880 | 0.78 | CARM1 (0.50) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL12719804 | 0.78 | — | — | |
| SCHEMBL20234635 | 0.78 | CARM1 (0.65) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL13602691 | 0.78 | CYP2D6 (0.37) | SIGMAR1HRH3 | |
| SCHEMBL13966102 | 0.77 | CARM1 (0.42) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL82611 | 0.77 | CARM1 (0.48) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL1196444 | 0.75 | CARM1 (0.56) | CARM1PRMT6PRMT1PRMT8SIGMAR1 | |
| SCHEMBL23828682 | 0.74 | CARM1 (0.60) | CARM1PRMT6PRMT1PRMT8SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2284172-A1 | Immunomodulating heterocyclic compounds | MediGene Ltd. (GB) | 2011-02-16 | — | — | EP | disclosed |