SCHEMBL1286060

SCHEMBL1286060

CCCCCCNC(=S)SCC

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.48
CASP2 P42575 1/20 0.44
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
NAAA Q02083 1/20 0.41
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
GBA1 P04062 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30747831 0.98 EPHX1 (0.47) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL1286386 0.98 EPHX1 (0.45) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL1286347 0.91 EPHX1 (0.40) EPHX1KEAP1NFE2L2
SCHEMBL27627323 0.89 MEN1 (0.39) EPHX1KEAP1NFE2L2
SCHEMBL23111738 0.88 EPHX1 (0.48) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL10804335 0.88 EPHX1 (0.48) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL10798027 0.88 EPHX1 (0.48) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL28883654 0.86 KEAP1 (0.50) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL28359053 0.86 KEAP1 (0.50) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL28764966 0.86 EPHX1 (0.47) EPHX1CASP2ZDHHC20ZDHHC2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2625159-B1 PROCESS FOR INHIBITING UNWANTED FREE-RADICAL POLYMERIZATION OF ACRYLIC ACID PRESENT IN A LIQUID PHASE P BASF SE (DE) 2024-10-02 EP disclosed
CN-103189443-B Rubber combination and manufacture method thereof and tire BRIDGESTONE CO.,LTD. (JP) 2016-03-09 CN disclosed
US-9212122-B2 Process for inhibiting unwanted free-radical polymerization of acrylic acid present in a liquid phase P BASF SE (DE) 2015-12-15 US disclosed
US-9096513-B2 2015-08-04 US disclosed
CN-103502405-B Zinc dithiocarbamate lubricating oil additives VANDERBILT CO R T 2015-03-25 CN disclosed
CN-103502405-A Zinc dithiocarbamate lubricating oil additives VANDERBILT CO R T 2014-01-08 CN disclosed
CN-102414269-B Rubber composition and pneumatic tire BRIDGESTONE CORP 2013-10-02 CN disclosed
EP-2625159-A1 PROCESS FOR INHIBITING UNWANTED FREE-RADICAL POLYMERIZATION OF ACRYLIC ACID PRESENT IN A LIQUID PHASE P BASF SE (DE) 2013-08-14 EP disclosed
CN-103189443-A Rubber composition and method of producing same, and tire BRIDGESTONE CORP 2013-07-03 CN disclosed
CN-101589100-B Rubber composition and tire using the same BRIDGESTONE CORP 2013-03-20 CN disclosed
WO-2012045738-A1 PROCESS FOR INHIBITING UNWANTED FREE-RADICAL POLYMERIZATION OF ACRYLIC ACID PRESENT IN A LIQUID PHASE P BASF SE (DE) 2012-04-12 WO disclosed
US-20120085969-A1 PROCESS FOR INHIBITING UNWANTED FREE-RADICAL POLYMERIZATION OF ACRYLIC ACID PRESENT IN A LIQUID PHASE P BASF SE (DE) 2012-04-12 US disclosed
CN-102414269-A Rubber composition and pneumatic tire BRIDGESTONE CORP 2012-04-11 CN disclosed
CN-101589100-A Rubber combination and the tire that uses it BRIDGESTONE CORP (JP) 2009-11-25 CN disclosed