Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.70 |
| ▸ | FAP | Q12884 | 10/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.65 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.65 |
| ▸ | HRH2 | P25021 | 1/20 | 0.65 |
| ▸ | MC4R | P32245 | 1/20 | 0.65 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.65 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.65 |
| ▸ | GHSR | Q92847 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17036591 | 0.90 | DPP4 (0.72) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL3919837 | 0.89 | DPP4 (0.70) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL18344002 | 0.89 | DPP4 (0.70) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL29350672 | 0.89 | DPP4 (0.70) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL18343936 | 0.89 | DPP4 (0.70) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL8266601 | 0.88 | DPP4 (0.57) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL16416909 | 0.87 | DPP4 (0.68) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL29456463 | 0.84 | DPP4 (0.64) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL20296912 | 0.84 | DPP4 (0.64) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL15083818 | 0.84 | DPP4 (0.85) | DPP4FAPCHRM1POU2F2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014097314-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LINAGLIPTIN | MYLAN LABORATORIES LTD (IN) | 2014-06-26 | — | — | WO | disclosed |
| EP-2287164-A1 | Process for the manufacture of chiral 8-(3-aminopiperidin-1-yl)-xanthines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-02-23 | — | — | EP | disclosed |