Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | LIPC | P11150 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25975127 | 0.81 | OR51E2 (0.47) | CFTRRXFP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL12894745 | 0.81 | CFTR (0.57) | CFTRRXFP1CES2KDM4EMAPT | |
| SCHEMBL3738491 | 0.80 | CFTR (0.54) | CFTRCES2KDM4EMAPTLMNA | |
| SCHEMBL22263091 | 0.79 | CFTR (0.73) | CFTRCES2KDM4EMAPTALDH1A1 | |
| SCHEMBL23141323 | 0.79 | CFTR (0.52) | CFTRCES2KDM4EMAPTLMNA | |
| SCHEMBL22519245 | 0.79 | KCNK2 (0.43) | CFTRRXFP1KDM4EMAPTLMNA | |
| SCHEMBL3744782 | 0.78 | CFTR (0.55) | CFTRCES2KDM4EHPGDKDM1A | |
| SCHEMBL26930977 | 0.78 | TAS2R14 (0.48) | CFTRRXFP1KDM4EMAPTLMNA | |
| SCHEMBL26930895 | 0.78 | CFTR (0.48) | CFTRRXFP1CES2KDM4EMAPT | |
| SCHEMBL26931075 | 0.78 | CFTR (0.48) | CFTRRXFP1CES2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947500-B1 | SULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2011-02-23 | — | — | EP | disclosed |