Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12864139 | 0.93 | KDM4E (0.43) | KDM4EATML3MBTL1MEN1LMNA | |
| SCHEMBL12864150 | 0.91 | L3MBTL1 (0.33) | KDM4EATML3MBTL1LMNAMAPT | |
| SCHEMBL19008287 | 0.90 | KDM4E (0.40) | KDM4EATML3MBTL1MEN1LMNA | |
| SCHEMBL19008304 | 0.90 | KDM4E (0.40) | KDM4EATML3MBTL1MEN1LMNA | |
| SCHEMBL19008291 | 0.89 | KDM4E (0.42) | KDM4EATML3MBTL1MEN1LMNA | |
| SCHEMBL26154323 | 0.89 | KDM4E (0.42) | KDM4EATML3MBTL1MEN1LMNA | |
| SCHEMBL2606158 | 0.87 | KDM4E (0.40) | KDM4EATML3MBTL1MEN1LMNA | |
| SCHEMBL24976651 | 0.87 | KDM4E (0.40) | KDM4EATML3MBTL1MEN1LMNA | |
| SCHEMBL15858705 | 0.87 | KDM4E (0.40) | KDM4EATML3MBTL1MEN1LMNA | |
| SCHEMBL31630296 | 0.87 | KDM4E (0.40) | KDM4EATML3MBTL1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361638-B2 | Fluorine derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-8361638-B2 | Fluorine derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20110037027-A1 | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20110037027-A1 | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110037027-A1 | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | SLCO4C1, CTCF, AFF2 | KDM4E 1747/4885ATM 2324/4885L3MBTL1 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.