SCHEMBL12866242

SCHEMBL12866242

CCN1/C(=C/C=C/c2ccc(O)c(OC=O)c2)Sc2c1ccc1ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 6/20 0.42
BACE1 P56817 1/20 0.38
PRMT5 O14744 1/20 0.37
CARM1 Q86X55 1/20 0.37
PRMT8 Q9NR22 1/20 0.37
ABCG2 Q9UNQ0 1/20 0.37
MAPT P10636 5/20 0.37
APP P05067 1/20 0.37
PDE4B Q07343 1/20 0.37
XDH P47989 1/20 0.36
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
NPC1 O15118 2/20 0.35
ALDH1A1 P00352 2/20 0.35
RAB9A P51151 1/20 0.35
ATM Q13315 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12866251 0.89 PRMT1 (0.42) PRMT1BACE1PRMT5CARM1PRMT8
SCHEMBL12866304 0.87 PRMT1 (0.47) PRMT1PRMT5CARM1PRMT8ABCG2
SCHEMBL15235467 0.87 PRMT1 (0.43) PRMT1BACE1PRMT5CARM1PRMT8
SCHEMBL12880703 0.84 PRMT1 (0.43) PRMT1PRMT5CARM1PRMT8ABCG2
SCHEMBL12866299 0.77 PRMT1 (0.45) PRMT1BACE1PRMT5CARM1PRMT8
SCHEMBL12866231 0.74 PRMT1 (0.54) PRMT1BACE1PRMT5PRMT8ABCG2
SCHEMBL12866232 0.74 PRMT1 (0.51) PRMT1BACE1PRMT5PRMT8ABCG2
SCHEMBL12894790 0.70 ABCG2 (0.37) PRMT1BACE1ABCG2MAPTMEN1
SCHEMBL10035991 0.68 PRMT1 (0.73) PRMT1PRMT5CARM1PRMT8MAPT
SCHEMBL16867335 0.68 PRMT1 (0.73) PRMT1PRMT5CARM1PRMT8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338700-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-20110030801-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110031446-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed