SCHEMBL12866251

SCHEMBL12866251

COCCN1/C(=C/C=C/c2ccc(O)c(OC=O)c2)Sc2c1ccc1ccccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 3/20 0.42
PRMT5 O14744 1/20 0.39
CARM1 Q86X55 1/20 0.39
PRMT8 Q9NR22 1/20 0.39
BACE1 P56817 3/20 0.38
ABCG2 Q9UNQ0 2/20 0.37
HSD17B3 P37058 1/20 0.37
APP P05067 1/20 0.37
MAPT P10636 1/20 0.37
XDH P47989 1/20 0.36
DNMT1 P26358 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
GAA P10253 1/20 0.34
TXNRD1 Q16881 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12866242 0.89 PRMT1 (0.42) PRMT1PRMT5CARM1PRMT8BACE1
SCHEMBL12866299 0.89 PRMT1 (0.45) PRMT1PRMT5CARM1PRMT8BACE1
SCHEMBL12866304 0.77 PRMT1 (0.47) PRMT1PRMT5CARM1PRMT8ABCG2
SCHEMBL15235467 0.77 PRMT1 (0.43) PRMT1PRMT5CARM1PRMT8BACE1
SCHEMBL12880703 0.74 PRMT1 (0.43) PRMT1PRMT5CARM1PRMT8ABCG2
SCHEMBL12866232 0.71 PRMT1 (0.51) PRMT1PRMT5PRMT8BACE1ABCG2
SCHEMBL12894790 0.70 ABCG2 (0.37) PRMT1BACE1ABCG2MAPTMEN1
SCHEMBL20115623 0.66 PRMT1 (0.37) PRMT1PRMT5CARM1PRMT8CYP1A2
SCHEMBL12866231 0.66 PRMT1 (0.54) PRMT1PRMT5PRMT8BACE1ABCG2
SCHEMBL12866229 0.64 XDH (0.43) APPMAPTXDHDNMT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338700-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-20110030801-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110031446-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed