SCHEMBL1286889

SCHEMBL1286889

CCCCC[Si](C)(C)OCC

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
THRB P10828 1/20 0.35
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31299234 0.97 TSHR (0.40) TSHRTHRBLMNA
SCHEMBL31299153 0.97 TSHR (0.40) TSHRTHRBLMNA
SCHEMBL31299121 0.97 TSHR (0.40) TSHRTHRBLMNA
SCHEMBL5570788 0.97 TSHR (0.40) TSHRTHRBLMNA
SCHEMBL31299139 0.97 TSHR (0.40) TSHRTHRBLMNA
SCHEMBL5574602 0.97 TSHR (0.40) TSHRTHRBLMNA
SCHEMBL4534251 0.97 TSHR (0.40) TSHRTHRBLMNA
SCHEMBL9253777 0.97 TSHR (0.40) TSHRTHRBLMNA
SCHEMBL3149888 0.97 TSHR (0.40) TSHRTHRBLMNA
SCHEMBL13480342 0.97 TSHR (0.40) TSHRTHRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693727-A Catalyst for olefin polymerization and application thereof 中国石油化工股份有限公司 2023-09-05 CN disclosed
CN-116693728-A Solid catalyst component, preparation method thereof, olefin polymerization catalyst and application thereof 中国石油化工股份有限公司 2023-09-05 CN disclosed
WO-2023157943-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM FORMING COMPOSITION HAVING UNSATURATED BOND AND CYCLIC STRUCTURE 日産化学株式会社 2023-08-24 WO disclosed
CN-109641430-B Photocatalyst laminate 信越化学工业株式会社 2022-03-11 CN disclosed
EP-3505343-B1 PHOTOCATALYST LAMINATE SHINETSU CHEMICAL CO (JP) 2022-01-12 EP disclosed
US-11161097-B2 Photocatalyst laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-11-02 US disclosed
US-10912786-B2 Silyl monomers capable of multimerizing in an aqueous solution, and methods of using same CORNELL UNIVERSITY (US) 2021-02-09 US disclosed
EP-3178876-B1 INORGANIC PARTICLE-POLYSILOXANE COMPOSITE, DISPERSION AND SOLID MATERIAL CONTAINING THE COMPOSITE, AND MAKING METHOD SHINETSU CHEMICAL CO (JP) 2020-10-21 EP disclosed
CN-105017841-B Organic solvent dispersion of titanium oxide solid solution particles, method of preparation and coating composition 信越化学工业株式会社 2020-01-17 CN disclosed
EP-3546497-A1 INORGANIC PARTICLE/SILOXANE COMPOSITE, METHOD FOR PRODUCING SAME, AND INORGANIC-PARTICLE-CONTAINING SILICONE COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 2019-10-02 EP disclosed
EP-1425350-A1 SILICA-COATED MIXED CRYSTAL OXIDE PARTICLE, PRODUCTION PROCESS THEREOF AND COSMETIC MATERIAL USING THE SAME SHOWA DENKO KABUSHIKI KAISHA (JP) 2004-06-09 EP disclosed
EP-1392773-A1 ROOM-TEMPERATURE-CURABLE SILICONE RUBBER COMPOSITION DOW CORNING TORAY SILICONE CO., LTD. (JP) 2004-03-03 EP disclosed
WO-2003025071-A1 SILICA-COATED MIXED CRYSTAL OXIDE PARTICLE, PRODUCTION PROCESS THEREOF AND COSMETIC MATERIAL USING THE SAME SHOWA DENKO K.K. (JP) 2003-03-27 WO disclosed
EP-1280848-A1 PROCESS FOR THE CONDENSATION OF COMPOUNDS HAVING SILICON BONDED HYDROXY OR ALKOXY GROUPS Dow Corning Corporation (US) 2003-02-05 EP disclosed
WO-2002096993-A1 ROOM-TEMPERATURE-CURABLE SILICONE RUBBER COMPOSITION DOW CORNING TORAY SILICONE CO.,LTD. (JP) 2002-12-05 WO disclosed
WO-2001079330-A1 PROCESS FOR THE CONDENSATION OF COMPOUNDS HAVING SILICON BONDED HYDROXY OR ALKOXY GROUPS DOW CORNING CORPORATION (US) 2001-10-25 WO disclosed
WO-2001012564-A1 COMBINED POROUS ORGANIC AND INORGANIC OXIDE MATERIALS PREPARED BY NON-IONIC SURFACTANT TEMPLATING ROUTE MICHIGAN STATE UNIVERSITY (US) 2001-02-22 WO disclosed
EP-0146138-B1 MELT MOLDING MATERIAL KURARAY CO., LTD. (JP) 1988-12-28 EP disclosed
US-4576988-A PACKAGING KURARAY CO., LTD. (JP) 1986-03-18 US disclosed
EP-0146138-A2 Melt molding material KURARAY CO., LTD. (JP) 1985-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10912786-B2 Silyl monomers capable of multimerizing in an aqueous solution, and methods of using same STIM1, STAMBP, ILK TSHR 4770/4885THRB 4156/4885LMNA 588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.