Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.68 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.68 |
| ▸ | IL6 | P05231 | 11/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146626 | 0.88 | TLR7 (0.63) | TLR7NUDT1IL6 | |
| SCHEMBL1146255 | 0.87 | TLR7 (0.76) | TLR7NUDT1IL6 | |
| SCHEMBL20157166 | 0.86 | TLR7 (0.78) | TLR7NUDT1IL6 | |
| SCHEMBL1146548 | 0.84 | TLR7 (0.59) | TLR7NUDT1IL6 | |
| SCHEMBL12800931 | 0.83 | TLR7 (0.66) | TLR7NUDT1IL6 | |
| SCHEMBL15177505 | 0.83 | TLR7 (0.66) | TLR7NUDT1IL6 | |
| SCHEMBL15177525 | 0.83 | TLR7 (0.74) | TLR7NUDT1IL6 | |
| SCHEMBL1146347 | 0.83 | TLR7 (0.60) | TLR7NUDT1IL6 | |
| SCHEMBL1146668 | 0.83 | TLR7 (0.72) | TLR7NUDT1IL6 | |
| SCHEMBL1146666 | 0.83 | TLR7 (0.62) | TLR7NUDT1IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028715-A1 | NOVEL ADENINE COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028715-A1 | NOVEL ADENINE COMPOUND | NR0B2, NR0B1, BRD7 | TLR7 4/4885NUDT1 15/4885IL6 3123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.