NR0B2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL1914213	1.00	4/20
SCHEMBL1914215	1.00	4/20
SCHEMBL12257895	1.00	4/20
SCHEMBL12257896	1.00	4/20
SCHEMBL29604865	1.00	4/20
SCHEMBL12257833	0.83	4/20
SCHEMBL12309639	0.77	4/20
SCHEMBL2391090	0.74	4/20
SCHEMBL2391094	0.68	4/20
SCHEMBL2391144	0.64	4/20
SCHEMBL12257890	0.61	4/20
SCHEMBL3290498	0.60	4/20
SCHEMBL12257892	0.60	4/20
SCHEMBL12257902	0.57	4/20
SCHEMBL20018663	0.56	4/20
SCHEMBL12257900	0.55	4/20
SCHEMBL13310490	0.52	4/20
SCHEMBL11799645	0.48	4/20
SCHEMBL11799661	0.48	4/20
SCHEMBL2389152	0.80	3/20

Clinical trials — most relevant to NR0B2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Chronic Effects of Estrogen in Microcirculation	PHASE4	COMPLETED
Fulvestrant in Metastatic Breast Cancer	PHASE4	UNKNOWN
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room	PHASE2/PHASE3	COMPLETED
Effects of Advair® in Outpatients With Chronic Obstructive Pulmonary Disease (COPD) Acute Exacerbation	PHASE3	COMPLETED
N-DOSE AD: A Dose Optimization Trial of Nicotinamide Riboside in Alzheimer's Disease	PHASE2	COMPLETED
N-DOSE: A Dose Optimization Trial of Nicotinamide Riboside in Parkinson's Disease	PHASE2	COMPLETED
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients	PHASE2	COMPLETED
Preoperative Bexarotene Treatment for Cushing's Disease	PHASE1/PHASE2	UNKNOWN
Activity of Regorafenib in Combination With Chemotherapy in Patients With Advanced Biliary Tract Cancer	PHASE1/PHASE2	COMPLETED
A Window of Opportunity Study of Pre-operative Endocrine Therapy With and Without Prometrium in Postmenopausal Women With Early Stage Breast Hormone Receptor Positive (HR+) Human Epidermal Receptor 2 Negative (HER2-) Breast Cancer.	PHASE2	UNKNOWN
TNFSF11 Inhibition and Fertility: a Prospective Study	PHASE2	COMPLETED
Seviteronel in Combination With Chemotherapy in Androgen-receptor Positive Metastatic Triple-negative Breast Cancer	PHASE1/PHASE2	RECRUITING
Fibrates in Pediatric Cholestasis	PHASE2	COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
A Safety and Efficacy Study of SHR3680 in Metastatic Castration-Resistant Prostate Cancer Patients	PHASE1/PHASE2	UNKNOWN
Meclizine for Hepatocellular Carcinoma	PHASE1	COMPLETED
The Impact of Pharmacological and Electric Modulation of NMDA Pathway on the Cognitive Flexibility and Volitional Movement Preparation in Patients With Parkinson's Disease	nan	COMPLETED
RORC Genetic Polymorphism of Rheumatoid Arthritis	nan	COMPLETED
Steroid Treatment of Idiopathic Nephrotic Syndrome	nan	COMPLETED
Expression of Steroid Receptors in Endometrium	nan	COMPLETED
Can Dietary Phytoestrogens Slow Down Prostate Tumor Proliferation?	nan	UNKNOWN
Stress and Treatment Response in Puerto Rican Children With Asthma	nan	COMPLETED
The Locus Coeruleus, Norepinephrine and Cognitive Aging	nan	ACTIVE_NOT_RECRUITING
Study IL- 35 Level and Fibronectin Type Ⅲ Domain Containing Protein 5 \ Irsin (FNDC5 rs3480) Gene Variations in Chronic Hepatitis B.	nan	UNKNOWN
The Role of Programmed Death Ligand -1 (Pdl-1) in Lung Cancer	nan	COMPLETED
Transcripts with Retained H/ACA Box SnoRNA Sequences As Biomarkers for Estrogen Dependence in Lum-B Breast Carcinomas	nan	ACTIVE_NOT_RECRUITING
The Impact of Selective Vitamin D Receptor Activation on Clinical Outcomes in Septic Patients	nan	NOT_YET_RECRUITING
Clinical and Basic Research on the Necessity of Scar Tissue Resection During Intrauterine Adhesions	nan	UNKNOWN
Studying Dexamethasone and Prednisone Sensitivity in Samples From Younger Patients With High-Risk B-Cell Precursor Acute Lymphoblastic Leukemia	nan	COMPLETED
Prognostic Value of Vitamin D Levels in Egyptian Females With Breast Cancer	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a NR0B2 binder may also engage these)

Protein	Name	Similarity
Q62227	—	1.000	Q62227 →
P97947	—	1.000	P97947 →
Q9QXZ7	—	0.988	Q9QXZ7 →
NR2E3	Photoreceptor-specific nuclear receptor	0.986	landscape →
Q9TTF0	—	0.985	Q9TTF0 →
A4FU01	—	0.985	A4FU01 →
Q80VA5	—	0.984	Q80VA5 →
P43136	—	0.984	P43136 →
Q5QJV7	—	0.984	Q5QJV7 →
Q86XR2	—	0.984	Q86XR2 →
O75064	—	0.983	O75064 →
P97680	—	0.983	P97680 →
Q921Q7	—	0.982	Q921Q7 →
Q3U0V2	—	0.982	Q3U0V2 →
Q6QMY5	—	0.982	Q6QMY5 →
Q6PDZ2	—	0.982	Q6PDZ2 →
Q9EQR6	—	0.981	Q9EQR6 →
Q5BK61	—	0.981	Q5BK61 →
Q6F5E8	—	0.981	Q6F5E8 →
Q68EF8	—	0.981	Q68EF8 →
A1L3T7	—	0.981	A1L3T7 →
Q3V3V9	—	0.981	Q3V3V9 →
Q8BXP5	—	0.981	Q8BXP5 →
P33076	—	0.980	P33076 →
Q1JPD6	—	0.980	Q1JPD6 →
P33242	—	0.980	P33242 →
O09017	—	0.980	O09017 →
Q8CFK6	—	0.980	Q8CFK6 →
P58660	—	0.980	P58660 →
Q7Z614	—	0.980	Q7Z614 →