Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.70 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287281 | 0.90 | PRMT1 (0.83) | ALDH1A1GAATP53PRMT1TBXA2R | |
| SCHEMBL407477 | 0.89 | ALDH1A1 (1.00) | ALDH1A1GAATP53PRMT1TBXA2R | |
| SCHEMBL17372561 | 0.88 | ALDH1A1 (0.79) | ALDH1A1GAATP53PRMT1TMEM97 | |
| SCHEMBL13889021 | 0.86 | ALDH1A1 (0.81) | ALDH1A1GAATP53PRMT1TAAR1 | |
| SCHEMBL10453016 | 0.85 | ALDH1A1 (0.74) | ALDH1A1GAATP53PRMT1TMEM97 | |
| SCHEMBL1287459 | 0.85 | ALDH1A1 (0.74) | ALDH1A1GAATP53TBXA2RMEN1 | |
| SCHEMBL1287382 | 0.84 | TAAR1 (0.82) | ALDH1A1GAATP53PRMT1MEN1 | |
| SCHEMBL3913371 | 0.84 | ALDH1A1 (0.79) | ALDH1A1GAATP53PRMT1TAAR1 | |
| SCHEMBL28808214 | 0.84 | ALDH1A1 (0.79) | ALDH1A1GAATP53MEN1KMT2A | |
| SCHEMBL10460529 | 0.84 | ALDH1A1 (0.72) | ALDH1A1GAATP53TBXA2RMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |