SCHEMBL12873199

SCHEMBL12873199

c1ccc(N2c3ccccc3Cc3cc4c(-c5ccc6ccccc6c5)c5cc(N6c7ccccc7Cc7ccccc76)ccc5c(-c5ccc6ccccc6c5)c4cc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.38
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
HSP90AA1 P07900 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12873201 0.97 HPGD (0.36) HPGDALDH1A1LMNACYP1A2CYP2C9
SCHEMBL13008985 0.92 HSP90AA1 (0.36) HPGDHSP90AA1ALDH1A1LMNACYP1A2
SCHEMBL13009390 0.92 HSP90AA1 (0.36) HPGDHSP90AA1ALDH1A1LMNACYP1A2
SCHEMBL12873197 0.91 HPGD (0.33) HPGD
SCHEMBL13008787 0.91 HPGD (0.35) HPGDHSP90AA1ALDH1A1LMNACYP1A2
SCHEMBL13009395 0.91 HPGD (0.35) HPGDHSP90AA1ALDH1A1LMNACYP1A2
SCHEMBL13009236 0.91 HSP90AA1 (0.35) HPGDHSP90AA1ALDH1A1LMNACYP1A2
SCHEMBL13009318 0.90 ESR1 (0.35) HPGDHSP90AA1ALDH1A1LMNACYP1A2
SCHEMBL13426984 0.90 HPGD (0.35) HPGDHSP90AA1ALDH1A1LMNACYP1A2
SCHEMBL13426994 0.88 ESR1 (0.36) HPGDHSP90AA1ALDH1A1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9045419-B2 Condensed-cyclic compound and organic light emitting diode having organic layer including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-02 US disclosed
US-9045419-B2 Condensed-cyclic compound and organic light emitting diode having organic layer including the same SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-02 US disclosed
US-20110031484-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE HAVING ORGANIC LAYER INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-02-10 US disclosed
US-20110031484-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE HAVING ORGANIC LAYER INCLUDING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110031484-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE HAVING ORGANIC LAYER INCLUDING THE SAME CRY1, CCNL2, CCNT1 HPGD 2260/4885ADRA2A 3785/4885ADRA2B 3670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.