Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 4/20 | 0.57 |
| ▸ | CCNK | O75909 | 1/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 19/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1192562 | 0.91 | CCNT1 (0.68) | CDK9CCNKCCNT1 | |
| SCHEMBL1192303 | 0.88 | CDK9 (0.57) | CDK9CCNKCCNT1 | |
| SCHEMBL1191780 | 0.88 | CCNK (0.59) | CDK9CCNKCCNT1 | |
| SCHEMBL1192708 | 0.86 | CCNT1 (0.63) | CDK9CCNKCCNT1 | |
| SCHEMBL1192372 | 0.85 | CCNK (0.61) | CDK9CCNKCCNT1 | |
| SCHEMBL1191988 | 0.83 | CCNT1 (0.59) | CDK9CCNKCCNT1 | |
| SCHEMBL1439346 | 0.82 | CCNK (0.58) | CDK9CCNKCCNT1 | |
| SCHEMBL12898116 | 0.82 | CDK9 (0.63) | CDK9CCNKCCNT1 | |
| SCHEMBL1192532 | 0.81 | CCNT1 (0.72) | CDK9CCNKCCNT1 | |
| SCHEMBL1192424 | 0.81 | CCNT1 (0.71) | CDK9CCNKCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288076-A1 | HETEROARYL COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2014-09-25 | — | — | US | disclosed |
| US-8778951-B2 | Heteroaryl compounds and their uses | NOVARTIS AG (CH) | 2014-07-15 | — | — | US | disclosed |
| US-20130303507-A1 | SUBSTITUTED HETERO-BIARYL COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2013-11-14 | — | — | US | disclosed |
| US-20130172354-A1 | HETEROARYL COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2013-07-04 | — | — | US | disclosed |
| US-8415381-B2 | Heteroaryl compounds and their uses | NOVARTIS AG (CH) | 2013-04-09 | — | — | US | disclosed |
| US-20110028492-A1 | Heteroaryl Compounds and Their Uses | NOVARTIS AG (CH) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172354-A1 | HETEROARYL COMPOUNDS AND THEIR USES | CDK9, CDK19, CDK3 | CDK9 1/4885CCNK 39/4885CCNT1 76/4885 |
| US-20140288076-A1 | HETEROARYL COMPOUNDS AND THEIR USES | CDK9, CDK19, CDK3 | CDK9 1/4885CCNK 39/4885CCNT1 76/4885 |
| US-20110028492-A1 | Heteroaryl Compounds and Their Uses | CDK9, CDK19, CDK3 | CDK9 1/4885CCNK 39/4885CCNT1 76/4885 |
| US-20130303507-A1 | SUBSTITUTED HETERO-BIARYL COMPOUNDS AND THEIR USES | CDK9, CDK19, CDK3 | CDK9 1/4885CCNK 29/4885CCNT1 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.