Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147470 | 0.89 | PANK3 (0.59) | PANK3NPC1RAB9ATRPV1TRPM8 | |
| SCHEMBL12874947 | 0.87 | NPC1 (0.51) | PANK3NPC1RAB9ATRPV1MAPT | |
| SCHEMBL1147379 | 0.78 | TRPV1 (0.55) | PANK3NPC1RAB9ATRPV1MAPT | |
| SCHEMBL1147181 | 0.78 | EPHX2 (0.56) | PANK3MAPTEPHX2CNR1CNR2 | |
| SCHEMBL1147398 | 0.77 | NPC1 (0.61) | PANK3NPC1RAB9ATRPV1MAPT | |
| SCHEMBL5119901 | 0.77 | PANK3 (0.53) | PANK3NPC1RAB9ATRPV1TRPM8 | |
| SCHEMBL4813571 | 0.77 | EPHX2 (0.61) | TRPV1TRPM8MAPTEPHX2CNR1 | |
| SCHEMBL4813582 | 0.77 | EPHX2 (0.61) | TRPV1TRPM8MAPTEPHX2CNR1 | |
| Hydrochloric Acid SCHEMBL1160542 | 0.77 | TRPV1 (0.54) | PANK3NPC1RAB9ATRPV1MAPT | |
| Hydrochloric Acid SCHEMBL15387462 | 0.76 | NPC1 (0.60) | PANK3NPC1RAB9ATRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012602-A1 | PIPERIDINE DERIVATIVES AND THEIR USE TO TREAT OBESITY, DIABETES, DYSLIPIDEMIA AND ATHEROSCLEROSIS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-02-03 | — | — | WO | disclosed |