Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.78 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.78 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | POLA1 | P09884 | 1/20 | 0.61 |
| ▸ | POLG | P54098 | 1/20 | 0.61 |
| ▸ | FAP | Q12884 | 1/20 | 0.61 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.56 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3301357 | 0.88 | FGFR1 (0.78) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL13805638 | 0.88 | FGFR1 (0.78) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL28797052 | 0.88 | FGFR1 (0.74) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL12393103 | 0.88 | FGFR1 (0.82) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL173078 | 0.88 | FGFR1 (0.80) | FGFR1SLC22A6ABCB11POLA1POLG | |
| Adefovir SCHEMBL49373 | 0.88 | FGFR1 (1.00) | FGFR1SLC22A6ABCB11POLA1POLG | |
| Adefovir SCHEMBL29365535 | 0.88 | FGFR1 (1.00) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL29258953 | 0.87 | FGFR1 (0.77) | FGFR1SLC22A6ABCB11POLA1POLG | |
| Adefovir SCHEMBL3639260 | 0.87 | FGFR1 (0.97) | FGFR1SLC22A6ABCB11POLA1POLG | |
| Adefovir SCHEMBL439995 | 0.87 | FGFR1 (0.97) | FGFR1SLC22A6ABCB11POLA1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016044-A1 | NOVEL POLYMORPHS OF ADEFOVIR DIPIVOXIL | HETERO RESEARCH FOUNDATION (IN) | 2011-02-10 | — | — | WO | disclosed |