Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.94 |
| ▸ | MAOA | P21397 | 3/20 | 0.68 |
| ▸ | MAOB | P27338 | 3/20 | 0.68 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8955927 | 0.75 | MAOA (0.76) | ARMAOAMAOB | |
| SCHEMBL12525418 | 0.74 | AR (0.66) | ARPGR | |
| SCHEMBL10297754 | 0.74 | AR (0.71) | ARPGR | |
| SCHEMBL22168116 | 0.74 | AR (0.66) | ARPGR | |
| SCHEMBL2656706 | 0.74 | MAOA (0.73) | ARMAOAMAOB | |
| SCHEMBL8956123 | 0.74 | MAOA (0.77) | ARMAOAMAOB | |
| SCHEMBL3189585 | 0.74 | AR (0.68) | AR | |
| SCHEMBL21491120 | 0.74 | MAOA (0.69) | ARMAOAMAOBPGR | |
| SCHEMBL8607019 | 0.73 | AR (0.55) | ARMAOAMAOB | |
| SCHEMBL23890842 | 0.72 | AR (0.57) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011021645-A1 | BICYCLIC UREA DERIVATIVE OR PHARMACOLOGICALLY PERMITTED SALT THEREOF | 大日本住友製薬株式会社 (JP) | 2011-02-24 | — | — | WO | disclosed |