SCHEMBL12876204

SCHEMBL12876204

Cc1ccc(S(=O)(=O)N(C)CCC[N+](C)(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
POLB P06746 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
HTT P42858 1/20 0.50
MAPT P10636 2/20 0.49
MCOLN3 Q8TDD5 1/20 0.47
C5AR1 P21730 1/20 0.45
AGER Q15109 1/20 0.45
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
CA2 P00918 1/20 0.43
GLA P06280 1/20 0.42
HSD17B10 Q99714 2/20 0.42
ALOX15 P16050 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12875996 0.94 LMNA (0.48) LMNASMN1; SMN2POLBMEN1KMT2A
SCHEMBL18986533 0.86 LMNA (0.55) LMNASMN1; SMN2POLBMEN1KMT2A
SCHEMBL12169294 0.83 LMNA (0.52) LMNASMN1; SMN2POLBMEN1KMT2A
SCHEMBL12876230 0.82 LMNA (0.46) LMNASMN1; SMN2POLBMEN1KMT2A
SCHEMBL14002193 0.80 MCHR1 (0.60) LMNASMN1; SMN2POLBMEN1KMT2A
SCHEMBL8008989 0.80 MCHR1 (0.60) LMNASMN1; SMN2POLBMEN1KMT2A
SCHEMBL13531713 0.79 MAPT (0.50) LMNASMN1; SMN2POLBMEN1KMT2A
SCHEMBL10282765 0.79 MAPT (0.53) LMNASMN1; SMN2POLBMEN1KMT2A
SCHEMBL13445263 0.79 MAPT (0.53) LMNASMN1; SMN2POLBMEN1KMT2A
SCHEMBL16285233 0.79 MAPT (0.53) LMNASMN1; SMN2POLBKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110033203-A1 TONER, METHOD FOR MANUFACTURING THE TONER, DEVELOPER INCLUDING THE TONER, CONTAINER CONTAINING THE TONER, AND IMAGE FORMING METHOD AND APPARATUS AND PROCESS CARTRIDGE USING THE TONER WATANABE YOHICHIROH 2011-02-10 US disclosed