Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746290 | 0.89 | L3MBTL1 (0.62) | L3MBTL1STK17APRKCQMAPTALDH1A1 | |
| SCHEMBL3267339 | 0.88 | L3MBTL1 (0.67) | L3MBTL1STK17APRKCQMAPTALDH1A1 | |
| SCHEMBL12876599 | 0.82 | L3MBTL1 (0.71) | L3MBTL1STK17APRKCQMAPTALDH1A1 | |
| SCHEMBL5408700 | 0.81 | STK17A (0.80) | L3MBTL1STK17APRKCQMAPTGSK3B | |
| SCHEMBL1521779 | 0.81 | GSK3B (0.53) | L3MBTL1STK17APRKCQMAPTGSK3B | |
| SCHEMBL4191611 | 0.78 | L3MBTL1 (0.66) | L3MBTL1STK17APRKCQMAPTALDH1A1 | |
| SCHEMBL5419910 | 0.78 | STK17A (0.63) | L3MBTL1STK17APRKCQMAPTGSK3B | |
| SCHEMBL11676466 | 0.78 | L3MBTL1 (0.58) | L3MBTL1STK17APRKCQMAPTALDH1A1 | |
| SCHEMBL12876608 | 0.76 | L3MBTL1 (0.45) | L3MBTL1 | |
| SCHEMBL5975211 | 0.73 | L3MBTL1 (0.52) | L3MBTL1STK17APRKCQMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046131-A1 | PURINES AS PKC-THETA INHIBITORS | N.V. Organon and Pharmacopeia, LLC | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046131-A1 | PURINES AS PKC-THETA INHIBITORS | PRKCQ, PRKCE, PRKCH | L3MBTL1 3625/4885STK17A 393/4885PRKCQ 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.