Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2803174 | 0.96 | FFAR3 (0.50) | — | |
| Methylcyclopentane SCHEMBL4087874 | 0.83 | EPHX1 (0.44) | — | |
| Methylcyclopentane SCHEMBL4362497 | 0.83 | EPHX1 (0.44) | — | |
| SCHEMBL9502832 | 0.81 | — | — | |
| Bicarbonate SCHEMBL27382637 | 0.81 | EPHX1 (0.37) | — | |
| Acetamide SCHEMBL9143780 | 0.81 | — | — | |
| Carbamic Acid SCHEMBL11215146 | 0.81 | — | — | |
| Methacrylic Acid SCHEMBL3288565 | 0.81 | TDP1 (0.38) | — | |
| Acetic Acid SCHEMBL938460 | 0.81 | EPHX1 (0.48) | — | |
| Acetic Acid SCHEMBL4087167 | 0.81 | EPHX1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1283115-A | Composition for treating respiratory and skin diseases, comprising at least one leukotriene antagonist and at least one antihistamine | SCHERING CORP (US) | 2001-02-07 | — | — | CN | claimed |
| US-10842952-B2 | Dry powder inhaler | SIMA PATENT VE LISANSLAMA HIZMETLERI LTD. STI. (TR) | 2020-11-24 | — | — | US | disclosed |
| CN-105085428-B | Aromatic heterocyclic derivatives and its application on drug | 广东东阳光药业有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-106279138-B | Aromatic heterocyclic derivatives and its application in drug | 广东东阳光药业有限公司 | 2019-03-01 | — | — | CN | disclosed |
| US-20180264211-A1 | DRY POWDER INHALER | SIMA PATENT VE LISANSLAMA HIZMETLERI LTD. STI. (TR) | 2018-09-20 | — | — | US | disclosed |
| CN-105399698-B | Aromatic heterocyclic derivatives and its application in drug | 广东东阳光药业有限公司 | 2018-08-10 | — | — | CN | disclosed |
| US-9849255-B2 | Inhalation device | BILGIC MAHMUT (TR) | 2017-12-26 | — | — | US | disclosed |
| EP-2782488-B1 | INHALATION DEVICE | BILGIC MAHMUT (TR) | 2017-10-25 | — | — | EP | disclosed |
| US-9795750-B2 | Dry powder inhaler | SIMA PATENT VE LISANSLAMA HIZMETLERI LTD. STI. (TR) | 2017-10-24 | — | — | US | disclosed |
| US-9795751-B2 | Dry powder inhaler | SIMA PATENT VE LISANSLAMA HIZMETLERI LTD. STI. (TR) | 2017-10-24 | — | — | US | disclosed |
| WO-2011129794-A1 | INHALATION DEVICE | BILGIC MAHMUT (TR) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011129791-A1 | INHALER COMPRISING BLISTER PACKAGE | BILGIC MAHMUT (TR) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011129788-A1 | USER-FRIENDLY DRY POWDER INHALER | BILGIC MAHMUT (TR) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011129789-A1 | DRY POWDER INHALER MOUTHPIECE BUTTON | BILGIC MAHMUT (TR) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011129786-A1 | INHALER USED FOR DELIVERY OF MEDICAMENT IN DRY POWDER FORM | BILGIC MAHMUT (TR) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011129795-A1 | DRY POWDER INHALER MOUTHPIECE BUTTON | BILGIC MAHMUT (TR) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011129793-A1 | DRY POWDER INHALER MOUTHPIECE BUTTON | BILGIC MAHMUT (TR) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011129785-A1 | DRY POWDER INHALER MOUTHPIECE BUTTON | BILGIC MAHMUT (TR) | 2011-10-20 | — | — | WO | disclosed |
| CN-1735601-A | Combination products with carboxylic acid derivatives that inhibit the binding of integrins to their receptors and other therapeutic compounds | SCHERING CORP (US) | 2006-02-15 | — | — | CN | disclosed |
| CN-1283115-A | Composition for treating respiratory and skin diseases, comprising at least one leukotriene antagonist and at least one antihistamine | SCHERING CORP (US) | 2001-02-07 | — | — | CN | disclosed |