Methacrylic Acid

Methacrylic Acid

SCHEMBL3288565

C=C(C)C(=O)O.CC1CC1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 5/20 0.34
KDM4E B2RXH2 3/20 0.34
EPHX1 P07099 2/20 0.33
ALOX15 P16050 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
TLR4 O00206 1/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
CYP1A2 P05177 1/20 0.30
CES2 O00748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL3287493 0.89 TDP1 (0.41) TDP1ALDH1A1EPHX1FFAR3LCK
Methacrylic Acid SCHEMBL3288616 0.85 EPHX1 (0.42) TDP1ALDH1A1EPHX1LMNATSHR
Methacrylic Acid SCHEMBL27462324 0.85 EPHX1 (0.42) TDP1ALDH1A1EPHX1LMNATSHR
Methacrylic Acid SCHEMBL3292360 0.85 EPHX1 (0.42) TDP1ALDH1A1EPHX1LMNATSHR
Methacrylic Acid SCHEMBL3291241 0.85 EPHX1 (0.42) TDP1ALDH1A1EPHX1LMNATSHR
Methacrylic Acid SCHEMBL31088246 0.81 TDP1 (0.42) TDP1ALDH1A1FFAR3LCKFYN
Methacrylic Acid SCHEMBL31088245 0.81 TDP1 (0.42) TDP1ALDH1A1FFAR3LCKFYN
Methacrylic Acid SCHEMBL27862740 0.81 ALDH1A1 (0.36) TDP1ALDH1A1
Acetic Acid SCHEMBL1287799 0.81
Methacrylic Acid SCHEMBL491341 0.80 TDP1 (0.53) TDP1ALDH1A1KDM4EALOX15FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3186226-B1 OXIME SULFONATE DERIVATIVES BASF SE (DE) 2020-06-17 EP disclosed
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2019-06-06 US disclosed
US-10241399-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent BASF SE (DE) 2019-03-26 US disclosed
US-10234761-B2 Oxime ester photoinitiators BASF SE (DE) 2019-03-19 US disclosed
EP-2668156-B1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2018-10-31 EP disclosed
US-20170260132-A1 OXIME SULFONATE DERIVATIVES BASF SE (DE) 2017-09-14 US disclosed
EP-3186226-A1 OXIME SULFONATE DERIVATIVES BASF SE (DE) 2017-07-05 EP disclosed
US-20160377977-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2016-12-29 US disclosed
EP-3019473-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2016-05-18 EP disclosed
US-9310677-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent BASF (DE) 2016-04-12 US disclosed
US-20160060214-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2016-03-03 US disclosed
WO-2016030790-A1 OXIME SULFONATE DERIVATIVES BASF SE (DE) 2016-03-03 WO disclosed
WO-2015004565-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2015-01-15 WO disclosed
EP-2668156-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2013-12-04 EP disclosed
US-20130308219-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2013-11-21 US disclosed
WO-2012101245-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2012-08-02 WO disclosed
US-7713680-B2 Radiation sensitive resin composition for forming a protective film, method of forming a protective film from the composition, liquid crystal display device and solid-state image sensing device JSR CORPORATION (JP) 2010-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10234761-B2 Oxime ester photoinitiators C9, C5, CBR3 TDP1 3900/4885ALDH1A1 2225/4885KDM4E 721/4885
US-20160377977-A1 OXIME ESTER PHOTOINITIATORS C5, C9, CBR3 TDP1 3904/4885ALDH1A1 2223/4885KDM4E 707/4885
US-10241399-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent SULT1E1, COX6B1, SULT1A1 TDP1 2916/4885ALDH1A1 776/4885KDM4E 81/4885
US-20170260132-A1 OXIME SULFONATE DERIVATIVES CBR3, CBR1, C1R TDP1 3750/4885ALDH1A1 1495/4885KDM4E 2891/4885
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT SULT1E1, COX6B1, SULT1A1 TDP1 2916/4885ALDH1A1 776/4885KDM4E 81/4885
US-20160060214-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT SULT1E1, COX6B1, SULT1A1 TDP1 2916/4885ALDH1A1 776/4885KDM4E 81/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.