SCHEMBL1287901

SCHEMBL1287901

CCCCCCCCn1c2cc(Br)ccc2c2ccc(Br)cc21

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 20/20 0.52
PSEN2 P49810 20/20 0.52
APH1B Q8WW43 20/20 0.52
NCSTN Q92542 20/20 0.52
APH1A Q96BI3 20/20 0.52
PSENEN Q9NZ42 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14881829 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29419588 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29396488 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30301267 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL20051919 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL19896457 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL15206581 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30932203 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6365324 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL426686 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111100536-A Anti-aging ultraviolet curing composite conductive coating and preparation method thereof 宁波其兰文化发展有限公司 2020-05-05 CN claimed
CN-103951705-B A kind of take carbazole as the bipolarity small molecule host material with butterfly-like shape and the preparation method of core SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2016-04-13 CN claimed
CN-117946372-A D-A random conjugated polymer with photo-thermal conversion capability and preparation method and application thereof 中山大学 2024-04-30 CN disclosed
CN-111808126-B A-pi-D-pi-A type BODIPY small molecule photovoltaic material and preparation method and application thereof 大连理工大学 2022-05-13 CN disclosed
CN-111808126-A A-pi-D-pi-A type BODIPY micromolecule photovoltaic material and preparation method and application thereof 大连理工大学 2020-10-23 CN disclosed
WO-2020200681-A1 POLYMERIZATION METHOD RHEINISCH-WESTFÄLISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN (DE) 2020-10-08 WO disclosed
CN-111100536-A Anti-aging ultraviolet curing composite conductive coating and preparation method thereof 宁波其兰文化发展有限公司 2020-05-05 CN disclosed
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 US disclosed
US-9786848-B2 Nanofiber-based heterojunction approach for high photoconductivity on organic materials UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2017-10-10 US disclosed
EP-3225610-A1 METHOD FOR MANUFACTURING COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-10-04 EP disclosed
WO-2012051553-A2 NANOFIBER-BASED HETEROJUNCTION APPROACH FOR HIGH PHOTOCONDUCTIVITY ON ORGANIC MATERIALS UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2012-04-19 WO disclosed
WO-2012047330-A2 FLUORESCENT CARBAZOLE OLIGOMERS NANOFIBRIL MATERIALS FOR VAPOR SENSING UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2012-04-12 WO disclosed
WO-2012047330-A2 FLUORESCENT CARBAZOLE OLIGOMERS NANOFIBRIL MATERIALS FOR VAPOR SENSING UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2012-04-12 WO disclosed
CN-101885834-A Conjugated polymer containing 4,5-ethylene-2,7-carbazole as well as preparation method and application thereof UNIV SOUTH CHINA TECH 2010-11-17 CN disclosed
EP-2061825-A1 UNIVERSAL GRIGNARD METATHESIS POLYMERIZATION CARNEGIE MELLON UNIVERSITY (US) 2009-05-27 EP disclosed
WO-2008132103-A1 PENTAPHENYLENE DERIVATIVES AS PHOTOSENSITIZERS IN SOLAR CELLS BASF SE (DE) 2008-11-06 WO disclosed
US-20080146754-A1 UNIVERSAL GIRNARD METATHESIS POLYMERIZATION CARNEGIE MELLON UNIVERSITY 2008-06-19 US disclosed
US-20080146754-A1 UNIVERSAL GIRNARD METATHESIS POLYMERIZATION CARNEGIE MELLON UNIVERSITY 2008-06-19 US disclosed
WO-2008028166-A1 UNIVERSAL GRIGNARD METATHESIS POLYMERIZATION CARNEGIE MELLON UNIVERSITY (US) 2008-03-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY ZC3HAV1, ZC3HAV1L, GTF3C3 PSEN1 4699/4885PSEN2 4790/4885APH1B 4144/4885
US-10421779-B2 Carbazole compound having anti-virus activity ZC3HAV1, ZC3HAV1L, GTF3C3 PSEN1 4699/4885PSEN2 4790/4885APH1B 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.