SCHEMBL426686

SCHEMBL426686

CCCCCCCCCCCCn1c2cc(Br)ccc2c2ccc(Br)cc21

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 20/20 0.52
PSEN2 P49810 20/20 0.52
APH1B Q8WW43 20/20 0.52
NCSTN Q92542 20/20 0.52
APH1A Q96BI3 20/20 0.52
PSENEN Q9NZ42 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14881829 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29419588 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29396488 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30301267 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL20051919 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1287901 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL19896457 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL15206581 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30932203 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6365324 1.00 PSEN1 (0.52) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050119491-A1 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof SHEFFIELD, THE UNIVERSITY OF (GB) 2005-06-02 US claimed
EP-1453802-A1 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF THE UNIVERSITY OF SHEFFIELD (GB) 2004-09-08 EP claimed
WO-2003050086-A1 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF THE UNIVERSITY OF SHEFFIELD (GB) 2003-06-19 WO claimed
CN-115746019-A Small molecule hole transport material, preparation method, application and perovskite battery 南京信息职业技术学院 2023-03-07 CN disclosed
CN-109796582-B Three-component fluorescent polymer and preparation method thereof, and fluorescent sensor and application thereof 吉林大学 2020-05-12 CN disclosed
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 US disclosed
EP-2657226-B1 ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHODS AND USES THEREOF OCEAN S KING LIGHTING SCIENCE&TECHNOLOGY CO LTD (CN) 2016-03-09 EP disclosed
US-9112157-B2 Hole transport materials including OLED applications SOLVAY USA, INC. (US) 2015-08-18 US disclosed
US-9112157-B2 Hole transport materials including OLED applications SOLVAY USA, INC. (US) 2015-08-18 US disclosed
US-9112157-B2 Hole transport materials including OLED applications SOLVAY USA, INC. (US) 2015-08-18 US disclosed
US-20130225782-A1 ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHODS AND USES THEREOF OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2013-08-29 US disclosed
US-20130225782-A1 ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHODS AND USES THEREOF OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2013-08-29 US disclosed
US-20130225782-A1 ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHODS AND USES THEREOF OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2013-08-29 US disclosed
US-8519068-B2 Conductive polymer containing carbazole, and organic photovoltaic device using same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2013-08-27 US disclosed
CN-102405247-A Conductive polymer containing carbazole, and organic photovoltaic device using same KOREA RES INST CHEM TECH 2012-04-04 CN disclosed
US-20120018715-A1 CONDUCTIVE POLYMER CONTAINING CARBAZOLE, AND ORGANIC PHOTOVOLTAIC DEVICE USING SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2012-01-26 US disclosed
US-20050119491-A1 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof SHEFFIELD, THE UNIVERSITY OF (GB) 2005-06-02 US disclosed
EP-1453802-A1 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF THE UNIVERSITY OF SHEFFIELD (GB) 2004-09-08 EP disclosed
WO-2003050086-A1 2, 7 - SUBSTITUTED CARBAZOLES AND OLIGOMERS, POLYMERS AND CO-POLYMERS THEREOF THE UNIVERSITY OF SHEFFIELD (GB) 2003-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY ZC3HAV1, ZC3HAV1L, GTF3C3 PSEN1 4699/4885PSEN2 4790/4885APH1B 4144/4885
US-10421779-B2 Carbazole compound having anti-virus activity ZC3HAV1, ZC3HAV1L, GTF3C3 PSEN1 4699/4885PSEN2 4790/4885APH1B 4144/4885
US-20050119491-A1 2, 7-Substituted carbazoles and oligomers, polymers and co-polymers thereof CBR3, OR10J3, ORC3 PSEN1 3918/4885PSEN2 3170/4885APH1B 3539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.