Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | CFTR | P13569 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 3/20 | 0.44 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436835 | 1.00 | CYP2D6 (1.00) | CYP2D6CYP2C19CYP2C9CYP3A4CFTR | |
| SCHEMBL1288198 | 1.00 | CYP2D6 (1.00) | CYP2D6CYP2C19CYP2C9CYP3A4CFTR | |
| SCHEMBL6435292 | 0.92 | CYP2D6 (0.85) | CYP2D6CYP2C19CYP2C9CYP3A4CFTR | |
| SCHEMBL12033031 | 0.91 | CYP2D6 (0.83) | CYP2D6CYP2C19CYP2C9CYP3A4CFTR | |
| SCHEMBL6435048 | 0.91 | CYP2D6 (0.83) | CYP2D6CYP2C19CYP2C9CYP3A4CFTR | |
| SCHEMBL23386739 | 0.91 | CYP2D6 (0.83) | CYP2D6CYP2C19CYP2C9CYP3A4CFTR | |
| SCHEMBL1688350 | 0.90 | CYP2D6 (0.82) | CYP2D6CYP2C19CYP2C9CYP3A4CFTR | |
| SCHEMBL6431743 | 0.89 | CYP2D6 (0.80) | CYP2D6CYP2C19CYP2C9CYP3A4CFTR | |
| SCHEMBL6431636 | 0.89 | CYP2D6 (0.80) | CYP2D6CYP2C19CYP2C9CYP3A4CFTR | |
| SCHEMBL20682768 | 0.88 | CYP2D6 (0.79) | CYP2D6CYP2C19CYP2C9CYP3A4CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140050793-A1 | Novel Compositions for Inhibiting Virus Entry and Promoting Virolysis, and Methods Thereof | DREXEL UNIVERSITY (US) | 2014-02-20 | — | — | US | claimed |
| WO-2012048033-A2 | NOVEL COMPOSITIONS FOR INHIBITING VIRUS ENTRY AND PROMOTING VIROLYISIS, AND METHODS THEREOF | DREXEL UNIVERSITY (US) | 2012-04-12 | — | — | WO | claimed |
| WO-2009011912-A1 | A COMPOSITION FOR TREATING HIV COMPRISING VIRUS-LIKE PARTICLES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-22 | — | — | WO | claimed |
| US-20220402899-A1 | COMPOUNDS FOR THE TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-12-22 | — | — | US | disclosed |
| WO-2021067528-A1 | COMPOUNDS FOR THE TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2021-04-08 | — | — | WO | disclosed |
| US-9114107-B2 | Compositions for inhibiting virus entry and promoting virolysis, and methods thereof | DREXEL UNIVERSITY (US) | 2015-08-25 | — | — | US | disclosed |
| US-20140050793-A1 | Novel Compositions for Inhibiting Virus Entry and Promoting Virolysis, and Methods Thereof | DREXEL UNIVERSITY (US) | 2014-02-20 | — | — | US | disclosed |
| WO-2013148067-A1 | 3,28-DISUBSTITUTED BETULINIC ACID DERIVATIVES AS ANTI-HIV AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-10-03 | — | — | WO | disclosed |
| WO-2012048033-A2 | NOVEL COMPOSITIONS FOR INHIBITING VIRUS ENTRY AND PROMOTING VIROLYISIS, AND METHODS THEREOF | DREXEL UNIVERSITY (US) | 2012-04-12 | — | — | WO | disclosed |
| WO-2010132334-A1 | 3,28-DISUBSTITUTED BETULINIC ACID DERIVATIVES AS ANTI-HIV AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2009011912-A1 | A COMPOSITION FOR TREATING HIV COMPRISING VIRUS-LIKE PARTICLES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-22 | — | — | WO | disclosed |
| EP-1257276-B1 | ANTIVIRAL AZAINDOLE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2005-12-28 | — | — | EP | disclosed |
| EP-1257276-A4 | ANTIVIRAL AZAINDOLE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2004-10-27 | — | — | EP | disclosed |
| US-6632819-B1 | HIV and AIDS | BRISTOL-MYERS SQUIBB COMPANY | 2003-10-14 | — | — | US | disclosed |
| US-20030181463-A1 | Antiviral azaindole derivatives | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2003-09-25 | — | — | US | disclosed |
| EP-1257276-A1 | ANTIVIRAL AZAINDOLE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6476034-B2 | AIDS THERAPY | BRISTOL-MYERS SQUIBB COMPANY | 2002-11-05 | — | — | US | disclosed |
| US-20020119982-A1 | Antiviral azaindole derivatives | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2002-08-29 | — | — | US | disclosed |
| US-20020061892-A1 | Antiviral azaindole derivatives | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2002-05-23 | — | — | US | disclosed |
| WO-2001062255-A1 | ANTIVIRAL AZAINDOLE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119982-A1 | Antiviral azaindole derivatives | ZC3HAV1, MAVS, AZI2 | CYP2D6 1648/4885CYP2C19 3101/4885CYP2C9 3477/4885 |
| US-20020061892-A1 | Antiviral azaindole derivatives | ZC3HAV1, MAVS, AZI2 | CYP2D6 1648/4885CYP2C19 3101/4885CYP2C9 3477/4885 |
| US-20220402899-A1 | COMPOUNDS FOR THE TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS | CD4, HAVCR2, ASGR1 | CYP2D6 630/4885CYP2C19 1504/4885CYP2C9 2127/4885 |
| US-20140050793-A1 | Novel Compositions for Inhibiting Virus Entry and Promoting Virolysis, and Methods Thereof | ZC3HAV1, ZC3HAV1L, CPN1 | CYP2D6 4766/4885CYP2C19 4709/4885CYP2C9 4560/4885 |
| US-20030181463-A1 | Antiviral azaindole derivatives | ZC3HAV1, MAVS, AZI2 | CYP2D6 1648/4885CYP2C19 3101/4885CYP2C9 3477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.