Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 4/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 2/20 | 1.00 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | TTR | P02766 | 1/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.67 |
| ▸ | KDM5A | P29375 | 1/20 | 0.64 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.64 |
| ▸ | SIRT3 | Q9NTG7 | 8/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | THRA | P10827 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30768209 | 0.96 | EYA3 (0.93) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL5419199 | 0.96 | EYA3 (0.93) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL11840583 | 0.92 | EYA3 (0.85) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL25389924 | 0.91 | EYA3 (0.82) | EYA3PTPN1SLC22A12TTRNR1H4 | |
| SCHEMBL28849127 | 0.90 | EYA3 (0.81) | EYA3PTPN1SLC22A12TTRNR1H4 | |
| SCHEMBL27992957 | 0.89 | EYA3 (0.80) | EYA3PTPN1TTRNR1H4KDM5A | |
| SCHEMBL3863077 | 0.88 | EYA3 (0.79) | EYA3PTPN1SLC22A12TTRNR1H4 | |
| SCHEMBL31314614 | 0.88 | EYA3 (0.79) | EYA3PTPN1TTRNR1H4KDM5A | |
| SCHEMBL31314577 | 0.88 | EYA3 (0.79) | EYA3PTPN1SLC22A12TTRNR1H4 | |
| SCHEMBL31314615 | 0.88 | EYA3 (0.79) | EYA3PTPN1TTRNR1H4KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567410-A | Preparation method of amiodarone hydrochloride for regulating heart rhythm | 山东科巢生物制药有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-117024383-A | Preparation method of amiodarone hydrochloride | 广州瑞尔医药科技有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-113278201-B | Preparation process of multifunctional silane coupling agent | 安徽沸点新材料有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-113278201-A | Preparation process of multifunctional silane coupling agent | 安徽沸点新材料有限公司 | 2021-08-20 | — | — | CN | claimed |
| CN-106946822-B | A kind of preparation method of 2- butyl -3- (4- hydroxy benzoyl) benzofuran | 华中科技大学 | 2019-03-05 | — | — | CN | claimed |
| CN-108440470-A | A kind of synthetic method of 2- butyl -3- (4- hydroxy benzoyls) benzofuran | 瑞孚信江苏药业股份有限公司 | 2018-08-24 | — | — | CN | claimed |
| CN-106946822-A | A kind of preparation method of 2 butyl 3 (4 hydroxy benzoyl) benzofurans | 华中科技大学 | 2017-07-14 | — | — | CN | claimed |
| CN-1858042-A | Synthetic process for 2-butyl-3(hydroxy 3,5-diiodo-benzoyl) benzofuran | ZHAO JINHAO (CN) | 2006-11-08 | — | — | CN | claimed |
| CN-120757523-A | Iodination method of amiodarone hydrochloride intermediate | 浙江恒康药业股份有限公司 | 2025-10-10 | — | — | CN | disclosed |
| CN-120518570-A | Synthesis method of 2-butyl-3- (4-hydroxybenzoyl) benzofuran | 合肥菁科生物科技有限公司 | 2025-08-22 | — | — | CN | disclosed |
| CN-120518570-A | Synthesis method of 2-butyl-3- (4-hydroxybenzoyl) benzofuran | 合肥菁科生物科技有限公司 | 2025-08-22 | — | — | CN | disclosed |
| CN-115844817-B | Amiodarone hydrochloride injection and preparation method thereof | 山东北大高科华泰制药有限公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-4448503-A1 | PROCESS FOR THE PREPARATION OF BENZOFURANS | Cambrex Profarmaco Milano S.r.l. (IT) | 2024-10-23 | — | — | EP | disclosed |
| CN-118496183-A | Synthesis method and application of amiodarone hydrochloride impurity F | 山东济坤生物制药有限公司 | 2024-08-16 | — | — | CN | disclosed |
| US-4766223-A | FROM ALKYL BENZOFURAN AND 4-METHOXYBENZOYL HALIDE; HYDROLYSIS, DEMETHYLATION | SANOFI (FR) | 1988-08-23 | — | — | US | disclosed |
| US-4661514-A | ANTIARRHYTHMIA AGENTS | SANOFI (FR) | 1987-04-28 | — | — | US | disclosed |
| US-4575513-A | ANTIARRHYTHMIA, ANGINA PECTORIS | SANOFI (FR) | 1986-03-11 | — | — | US | disclosed |
| US-4565828-A | CARDIOVASCULAR DISORDERS, ANTAGONIST OF CALCIUM | SANOFI (FR) | 1986-01-21 | — | — | US | disclosed |
| US-3983245-A | CORONARY VASODILATORS | SMITHKLINE CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
| US-3975537-A | SUBSTITUTED BENZOFURANS | SMITH KLINE (US) | 1976-08-17 | — | — | US | disclosed |