Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | PLK1 | P53350 | 7/20 | 0.66 |
| ▸ | MMP13 | P45452 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12893245 | 0.87 | ALDH1A1 (0.51) | HPGDTSHRHTTSMN1; SMN2PLK1 | |
| SCHEMBL19646821 | 0.84 | SMN1; SMN2 (0.68) | HPGDTSHRHTTSMN1; SMN2PLK1 | |
| SCHEMBL4069238 | 0.84 | MAPT (0.57) | HPGDTSHRHTTSMN1; SMN2PLK1 | |
| SCHEMBL10095152 | 0.84 | HSD17B10 (0.56) | HPGDTSHRHTTSMN1; SMN2PLK1 | |
| SCHEMBL13944298 | 0.84 | PLK1 (0.60) | HPGDTSHRHTTSMN1; SMN2PLK1 | |
| SCHEMBL277445 | 0.84 | PLK1 (0.51) | HPGDTSHRHTTSMN1; SMN2PLK1 | |
| SCHEMBL19899450 | 0.82 | SMN1; SMN2 (0.46) | HPGDTSHRHTTSMN1; SMN2PLK1 | |
| SCHEMBL22163899 | 0.82 | HPGD (0.66) | HPGDTSHRHTTSMN1; SMN2PLK1 | |
| SCHEMBL13649537 | 0.82 | HPGD (0.66) | HPGDTSHRHTTSMN1; SMN2PLK1 | |
| SCHEMBL12418676 | 0.81 | PLK1 (0.49) | HPGDTSHRHTTSMN1; SMN2PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269713-A1 | BRYOSTATIN ANALOGUES AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2011-11-03 | — | — | US | disclosed |
| US-7879953-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-7879953-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-20100297211-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2010-11-25 | — | — | US | disclosed |
| US-20100297211-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2010-11-25 | — | — | US | disclosed |
| US-7786249-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-7786249-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-7772359-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-7772359-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-7632914-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2009-12-15 | — | — | US | disclosed |
| US-7632914-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2009-12-15 | — | — | US | disclosed |
| US-20090012606-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2009-01-08 | — | — | US | disclosed |
| US-20090012606-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2009-01-08 | — | — | US | disclosed |
| US-20090012243-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2009-01-08 | — | — | US | disclosed |
| US-20090012243-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2009-01-08 | — | — | US | disclosed |
| US-20090012259-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2009-01-08 | — | — | US | disclosed |
| US-20090012259-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2009-01-08 | — | — | US | disclosed |
| US-7435788-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-7435788-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2008-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269713-A1 | BRYOSTATIN ANALOGUES AND METHODS OF MAKING AND USING THEREOF | PRKAR2B, PRKAR2A, PRKCH | HPGD 2235/4885TSHR 3430/4885HTT 2587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.