Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | AADAT | Q8N5Z0 | 6/20 | 0.47 |
| ▸ | GOT1 | P17174 | 1/20 | 0.47 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.47 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320121 | 0.87 | ACE (0.53) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL3870683 | 0.87 | ACE (0.53) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL199254 | 0.87 | ACE (0.53) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL4738589 | 0.82 | ANPEP (0.49) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL7443272 | 0.77 | HRH4 (0.42) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL7443268 | 0.77 | HRH4 (0.42) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL12153088 | 0.75 | ANPEP (0.45) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL4491852 | 0.73 | AADAT (0.51) | AADATGOT1KYAT1KYAT3ANPEP | |
| SCHEMBL12626584 | 0.73 | AADAT (0.51) | AADATGOT1KYAT1KYAT3ANPEP | |
| SCHEMBL13431286 | 0.72 | ACE (0.53) | OPRM1OPRD1ACEMMETACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884074-B2 | Compounds and methods for prevention and/or treatment of inflammation using the same | Ikaria Development Subsidiary Two, LLC (US) | 2011-02-08 | — | — | US | disclosed |