Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4499450 | 0.99 | CXCR1 (0.48) | CXCR1CXCR2POLBALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4505109 | 0.88 | RAD52 (0.50) | CXCR1CXCR2POLBALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4509152 | 0.86 | RAD52 (0.48) | CXCR1CXCR2POLBALDH1A1MAPK1 | |
| SCHEMBL1289484 | 0.85 | CHRM2 (0.56) | CXCR1CXCR2POLBALDH1A1MAPK1 | |
| SCHEMBL1289430 | 0.85 | ALDH1A1 (0.65) | POLBALDH1A1MAPK1RAD52KMT2A | |
| Hydrochloric Acid SCHEMBL4497754 | 0.84 | CXCR1 (0.53) | CXCR1CXCR2POLBALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4507915 | 0.84 | ALDH1A1 (0.67) | POLBALDH1A1MAPK1RAD52KMT2A | |
| Hydrochloric Acid SCHEMBL4505202 | 0.83 | ALDH1A1 (0.47) | CXCR1CXCR2POLBALDH1A1MAPK1 | |
| SCHEMBL1289354 | 0.83 | MKNK1 (0.50) | POLBALDH1A1MAPK1RAD52KMT2A | |
| SCHEMBL1289349 | 0.82 | POLB (0.58) | CXCR1CXCR2POLBALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |