SCHEMBL1289396

SCHEMBL1289396

C=CC(=O)OC(CCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C)C(O)CO

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5839405 0.90 HPGD (0.30) HPGDTSHR
SCHEMBL5837961 0.90 HPGD (0.30) HPGDTSHR
SCHEMBL5838686 0.86 TSHR (0.31) HPGDTSHR
SCHEMBL5838856 0.85
SCHEMBL1274033 0.82
Acrylic Acid Ethyl Ester SCHEMBL9241913 0.80 TSHR (0.38) HPGDTSHR
SCHEMBL12473420 0.78
SCHEMBL2773252 0.73
SCHEMBL8465842 0.73
SCHEMBL9302432 0.73 TSHR (0.37) HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11866531-B2 Oil-resistant lens material and ophthalmic devices Twenty Twenty Therapeutrics LLC (US) 2024-01-09 US disclosed
WO-2021067189-A1 OIL-RESISTANT LENS MATERIAL AND ELECTROWETTING OPHTHALMIC DEVICES VERILY LIFE SCIENCES LLC (US) 2021-04-08 WO disclosed
US-20210095063-A1 OIL-RESISTANT LENS MATERIAL AND OPHTHALMIC DEVICES VERILY LIFE SCIENCES LLC 2021-04-01 US disclosed
US-10752833-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2020-08-25 US disclosed
US-20190194535-A1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2019-06-27 US disclosed
US-10119070-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2018-11-06 US disclosed
US-9885883-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2018-02-06 US disclosed
US-20170088771-A1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2017-03-30 US disclosed
EP-2951620-B1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORP (JP) 2017-03-01 EP disclosed
US-9574067-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2017-02-21 US disclosed
US-20020198280-A1 Material for ocular lens MENICON CO., LTD. (JP) 2002-12-26 US disclosed
EP-1197782-A1 MATERIAL FOR OCULAR LENS MENICON CO., LTD. (JP) 2002-04-17 EP disclosed
EP-0434362-B1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution TOMEI SANGYO KK (JP) 1995-03-22 EP disclosed
EP-0294515-B1 Contact lens material MENICON CO LTD (JP) 1994-05-25 EP disclosed
US-5206298-A GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE TOMEI SANGYO KABUSHIKI KAISHA (JP) 1993-04-27 US disclosed
EP-0434362-A1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-26 EP disclosed
US-4814402-A VINYLPYRROLIDONE OR METHACRYLIC ACID AND SILICON CONTAINING METHACRYLATE MENICON CO., LTD. (JP) 1989-03-21 US disclosed
EP-0294515-A2 Contact lens material Menicon Co., Ltd. (JP) 1988-12-14 EP disclosed
US-4594401-A Oxygen permeable hard contact lens formed from styrene monomer containing a silyl or siloxane group SHIN-ETSU CHEMICAL CO., LTD. (JP) 1986-06-10 US disclosed
US-4433125-A COPOLYMER OF SILICON CONTAINING ACRYLATE OR METHACRYLATE, AND FLUOROALKYL ACRYLATE OR METHACRYLATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1984-02-21 US disclosed