⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367569 | 0.85 | — | — | |
| SCHEMBL9580483 | 0.81 | THRB (0.34) | — | |
| Acrylic Acid Ethyl Ester SCHEMBL9241913 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL2367736 | 0.79 | — | — | |
| SCHEMBL2770385 | 0.77 | LMNA (0.33) | — | |
| Methacrylic Acid SCHEMBL11039926 | 0.73 | — | — | |
| SCHEMBL1003039 | 0.73 | LMNA (0.35) | — | |
| SCHEMBL790520 | 0.72 | ALDH1A1 (0.30) | — | |
| SCHEMBL373574 | 0.72 | — | — | |
| SCHEMBL20437553 | 0.72 | USP2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114051497-A | Chromene compound and photochromic optical article | 株式会社德山 | 2022-02-15 | — | — | CN | disclosed |
| EP-1589367-B1 | PHOTOCHROMIC CONTACT LENS EXCELLING IN DECOLORING CHARACTERISTIC | MENICON CO LTD (JP) | 2019-03-13 | — | — | EP | disclosed |
| EP-2174966-A1 | OPTICAL MATERIAL AND OPHTHALMIC LENS MADE OF THE SAME | Menicon Co., Ltd. (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-1566684-B1 | LENS FOR EYE AND METHOD FOR MARKING THEREOF | MENICON CO LTD (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-7044598-B2 | Lens for eye and method for marking thereof | MENICON CO., LTD.. (JP) | 2006-05-16 | — | — | US | disclosed |
| US-20050243273-A1 | Photochromic contact lens having excellent discoloring characteristic | MENICON CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| EP-1589367-A1 | PHOTOCHROMIC CONTACT LENS EXCELLING IN DECOLORING CHARACTERISTIC | MENICON CO., LTD. (JP) | 2005-10-26 | — | — | EP | disclosed |