Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 6/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4511035 | 0.99 | ACP1 (0.66) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL1289411 | 0.92 | MAPK1 (0.57) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL1289434 | 0.92 | MAPK1 (0.71) | ACP1MAPK1TSHRALOX15TP53 | |
| Hydrochloric Acid SCHEMBL4511251 | 0.91 | MAPK1 (0.70) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL4498537 | 0.83 | PDE5A (0.58) | ACP1MAPK1MAPTNPSR1MEN1 | |
| SCHEMBL1687974 | 0.81 | HRH2 (0.51) | ACP1MAPK1TSHRALOX15TP53 | |
| SCHEMBL1289430 | 0.80 | ALDH1A1 (0.65) | ACP1MAPK1KMT2AALDH1A1POLB | |
| SCHEMBL12473363 | 0.79 | ALDH1A1 (0.60) | ACP1MAPK1KMT2AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL4507915 | 0.79 | ALDH1A1 (0.67) | ACP1MAPK1KMT2AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL4500478 | 0.78 | ALDH1A1 (0.62) | ACP1MAPK1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |