Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | TRIM58 | Q8NG06 | 2/20 | 0.42 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4493025 | 0.99 | MAPK1 (0.49) | MAPK1ALDH1A1RAD52KMT2APOLB | |
| SCHEMBL1289436 | 0.93 | MAPK1 (0.48) | MAPK1ALDH1A1RAD52KMT2APOLB | |
| Hydrochloric Acid SCHEMBL4498523 | 0.92 | MAPK1 (0.49) | MAPK1ALDH1A1RAD52KMT2APOLB | |
| SCHEMBL1289520 | 0.86 | FLT3 (0.53) | MAPK1ALDH1A1RAD52KMT2APOLB | |
| SCHEMBL1289430 | 0.85 | ALDH1A1 (0.65) | MAPK1ALDH1A1RAD52KMT2APOLB | |
| Hydrochloric Acid SCHEMBL4506872 | 0.85 | RAD52 (0.57) | MAPK1ALDH1A1RAD52KMT2APOLB | |
| SCHEMBL1289369 | 0.85 | FLT3 (0.57) | MAPK1ALDH1A1RAD52KMT2APOLB | |
| Hydrochloric Acid SCHEMBL4508209 | 0.85 | ALDH1A1 (0.53) | MAPK1ALDH1A1RAD52KMT2APOLB | |
| SCHEMBL1289349 | 0.85 | POLB (0.58) | MAPK1ALDH1A1RAD52KMT2APOLB | |
| Hydrochloric Acid SCHEMBL4507915 | 0.85 | ALDH1A1 (0.67) | MAPK1ALDH1A1RAD52KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |