SCHEMBL12894480

SCHEMBL12894480

CNC(=O)c1cc(C(=O)Nc2ccc(C)cc2)c(C(=O)O)cc1OC=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.45
▸ MEN1 O00255 5/20 0.45
▸ POLB P06746 3/20 0.45
▸ AHR P35869 1/20 0.45
▸ RAB9A P51151 6/20 0.41
▸ NPC1 O15118 5/20 0.41
▸ NFKB1 P19838 2/20 0.41
▸ NFKB2 Q00653 2/20 0.41
▸ RELA Q04206 2/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ MAPT P10636 5/20 0.40
▸ LMNA P02545 3/20 0.40
▸ GFER P55789 2/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ SMN1; SMN2 Q16637 4/20 0.40
▸ TP53 P04637 2/20 0.40
▸ HTT P42858 2/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ MAPK1 P28482 2/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12786217 1.00 KMT2A (0.45) KMT2AMEN1POLBAHRRAB9A
SCHEMBL12555547 0.94 MAPK1 (0.48) KMT2AMEN1POLBAHRRAB9A
SCHEMBL15468825 0.87 SCN10A (0.43) KMT2AMEN1GFERMAPK1ALDH1A1
SCHEMBL20253301 0.86 CYP1A2 (0.43) KMT2AMEN1POLBRAB9ANPC1
SCHEMBL12894460 0.86 NR1H4 (0.44) KMT2AMEN1POLBAHRRAB9A
SCHEMBL17298062 0.86 MAPK1 (0.52) KMT2AMEN1POLBNPC1L3MBTL1
SCHEMBL9885133 0.86 RAB9A (0.51) KMT2AMEN1POLBAHRRAB9A
SCHEMBL16273258 0.86 SCN8A (0.44) KMT2AMEN1POLBAHRRAB9A
SCHEMBL20202766 0.85 LCK (0.38) KMT2AMEN1POLBL3MBTL1MAPT
SCHEMBL18562064 0.83 NR1H4 (0.39) KMT2AMEN1POLBL3MBTL1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034474-B2 Fixing belt and fixing device CANON KABUSHIKI KAISHA (JP) 2015-05-19 — — US disclosed
US-20110045310-A1 FIXING BELT AND FIXING DEVICE CANON KABUSHIKI KAISHA (JP) 2011-02-24 — — US disclosed
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