Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.52 |
| ▸ | HTR1A | P08908 | 5/20 | 0.52 |
| ▸ | HTR2A | P28223 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
| ▸ | HTR2B | P41595 | 4/20 | 0.52 |
| ▸ | HTR1D | P28221 | 4/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.45 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | SPR | P35270 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12921572 | 0.89 | HTR2C (0.51) | HTR2CCYP2D6HTR1AHTR2ACYP1A2 | |
| SCHEMBL12895290 | 0.88 | HTR2A (0.41) | HTR2CCYP2D6HTR1AHTR2ACYP1A2 | |
| SCHEMBL12894457 | 0.82 | HTR2C (0.51) | HTR2CCYP2D6HTR1AHTR2ACYP1A2 | |
| SCHEMBL12894535 | 0.81 | HTR2C (0.53) | HTR2CCYP2D6HTR1AHTR2ACYP1A2 | |
| SCHEMBL15281780 | 0.81 | HTR2C (0.57) | HTR2CCYP2D6HTR1AHTR2ACYP1A2 | |
| SCHEMBL5108611 | 0.81 | HTR2C (0.57) | HTR2CCYP2D6HTR1AHTR2ACYP1A2 | |
| SCHEMBL15281771 | 0.81 | HTR2C (0.57) | HTR2CCYP2D6HTR1AHTR2ACYP1A2 | |
| SCHEMBL13756707 | 0.75 | ESR1 (0.42) | CYP2D6HTR2ACYP1A2CYP3A4NPSR1 | |
| SCHEMBL6981457 | 0.72 | HTR2C (0.77) | HTR2CCYP2D6HTR1AHTR2ACYP1A2 | |
| SCHEMBL19361707 | 0.71 | HTR2C (0.60) | HTR2CCYP2D6HTR1AHTR2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893084-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM CANADA LTD. (CA) | 2011-02-22 | — | — | US | disclosed |
| US-7576079-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2009-08-18 | — | — | US | disclosed |
| US-20090087409-A1 | Viral Polymerase Inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090087409-A1 | Viral Polymerase Inhibitors | NR2C2, NR4A1, MED25 | HTR2C 1081/4885CYP2D6 153/4885HTR1A 2078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.