Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.77 |
| ▸ | HTR1A | P08908 | 5/20 | 0.77 |
| ▸ | HTR2A | P28223 | 5/20 | 0.77 |
| ▸ | HTR2B | P41595 | 4/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.77 |
| ▸ | HTR1D | P28221 | 4/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.77 |
| ▸ | HTR1B | P28222 | 2/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.63 |
| ▸ | BLM | P54132 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396996 | 0.87 | HTR2C (1.00) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL29389055 | 0.87 | HTR2C (1.00) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL25331243 | 0.84 | HTR2C (0.69) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL14755631 | 0.84 | HTR2C (0.67) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL12563612 | 0.83 | HTR2C (0.68) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL14032315 | 0.83 | HTR2C (0.71) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL12039373 | 0.83 | HTR2C (0.71) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL22538964 | 0.83 | HTR2C (0.76) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL20340879 | 0.81 | HTR2A (0.74) | HTR2CHTR1AHTR2AHTR2BCYP2D6 | |
| SCHEMBL19067627 | 0.81 | HTR2A (0.61) | HTR2CHTR1AHTR2AHTR2BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220204497-A1 | NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME | DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2022-06-30 | — | — | US | disclosed |
| US-7345040-B2 | Reverse-turn mimetics and compositions and methods relating thereto | MYRIAD GENETICS, INC. (US) | 2008-03-18 | — | — | US | disclosed |
| EP-1268422-A1 | INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES | Bayer Aktiengesellschaft (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070687-A1 | INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204497-A1 | NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME | TPX2, AIMP2, CDYL2 | HTR2C 4405/4885HTR1A 4442/4885HTR2A 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.