SCHEMBL1289476

SCHEMBL1289476

O=CC(C=O)CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27679696 0.75 SLC22A6 (0.45)
SCHEMBL6442999 0.73
SCHEMBL14539493 0.73
SCHEMBL8169661 0.73
SCHEMBL2671585 0.73 TET2 (0.50)
SCHEMBL584099 0.72 SLC22A6 (0.56)
SCHEMBL6022478 0.71
SCHEMBL11700595 0.71
SCHEMBL1529128 0.71
SCHEMBL3328080 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0319927-A2 Method for preparing multilayered coated articles and the coated articles prepared by the method PPG INDUSTRIES, INC. (US) 1989-06-14 EP claimed
US-20160175288-A1 MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE ELIXIR MEDICAL CORPORATION 2016-06-23 US disclosed
US-20150164772-A1 Methods and Compositions to Impart Memory Effects onto Biosurfaces AVON PRODUCTS, INC. 2015-06-18 US disclosed
US-8946144-B2 Phosphonated glycopeptide and lipoglycopeptide antibiotics and uses thereof for the prevention and treatment of bone and joint infections THE MEDICINES COMPANY (US) 2015-02-03 US disclosed
EP-2790662-A1 METHODS AND COMPOSITIONS TO IMPART MEMORY EFFECTS ONTO BIOSURFACES Avon Products, Inc. (US) 2014-10-22 EP disclosed
US-20130230571-A1 MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE ELIXIR MEDICAL CORPORATION (US) 2013-09-05 US disclosed
EP-2624834-A1 MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE Elixir Medical Corporation (US) 2013-08-14 EP disclosed
WO-2013090316-A1 METHODS AND COMPOSITIONS TO IMPART MEMORY EFFECTS ONTO BIOSURFACES AVON PRODUCTS, INC. (US) 2013-06-20 WO disclosed
US-20130146080-A1 Methods and Compositions to Impart Memory Effects onto Biosurfaces AVON PRODUCTS, INC. (US) 2013-06-13 US disclosed
WO-2012047813-A1 MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE ELIXIR MEDICAL CORPORATION (US) 2012-04-12 WO disclosed
CN-102231969-A Macrocyclic lactone compounds and methods for their use ELIXIR MEDICAL CORP 2011-11-02 CN disclosed
EP-2352459-A1 MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE Elixir Medical Corporation (US) 2011-08-10 EP disclosed
US-20100113333-A1 PHOSPHONATED GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS TARGANTA THERAPEUTICS, INC. (CA) 2010-05-06 US disclosed
WO-2010040064-A1 MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE ELIXIR MEDICAL CORPORATION (US) 2010-04-08 WO disclosed
US-20100086579-A1 MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE ELIXIR MEDICAL CORPORATION (US) 2010-04-08 US disclosed
US-20080287396-A1 Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections TARGANTA THERAPEUTICA INC. (CA) 2008-11-20 US disclosed