SCHEMBL584099

SCHEMBL584099

O=C(O)CC(CC(=O)O)C(CC(=O)O)CC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.56
TDP1 Q9NUW8 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.50
TSHR P16473 2/20 0.47
GABRR1 P24046 2/20 0.45
LMNA P02545 2/20 0.45
FOLH1 Q04609 2/20 0.41
LDHA P00338 1/20 0.40
SRR Q9GZT4 1/20 0.40
ALKBH5 Q6P6C2 1/20 0.40
SUCNR1 Q9BXA5 1/20 0.40
EGLN1 Q9GZT9 1/20 0.40
MAPT P10636 1/20 0.39
FFAR3 O14843 1/20 0.38
GLRA1 P23415 1/20 0.38
SLC6A9 P48067 1/20 0.38
OR51E2 Q9H255 1/20 0.38
CACNB3 P54284 1/20 0.36
CACNA2D1 P54289 1/20 0.36
CACNA1C Q13936 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL22463070 0.96 TDP1 (0.59) SLC22A6TDP1SMN1; SMN2TSHRGABRR1
SCHEMBL27753421 0.84 SLC22A6 (0.43) SLC22A6TDP1SMN1; SMN2TSHRGABRR1
SCHEMBL7912646 0.82 SLC22A6 (0.47) SLC22A6TDP1SMN1; SMN2TSHRGABRR1
SCHEMBL5972500 0.80 CACNA2D1 (0.52) SLC22A6TDP1SMN1; SMN2MAPTCACNB3
SCHEMBL28354942 0.79 TDP1 (0.50) SLC22A6TDP1SMN1; SMN2TSHRGABRR1
SCHEMBL678102 0.79 SLC22A6 (0.45) SLC22A6TDP1SMN1; SMN2TSHRGABRR1
SCHEMBL5077882 0.79 SLC22A6 (0.45) SLC22A6TDP1SMN1; SMN2TSHRGABRR1
SCHEMBL5960145 0.79 SMN1; SMN2 (0.48) SLC22A6TDP1SMN1; SMN2TSHRGABRR1
SCHEMBL303998 0.79 SLC22A6 (0.53) SLC22A6TDP1SMN1; SMN2TSHRGABRR1
SCHEMBL21838442 0.77 TDP1 (0.72) SLC22A6TDP1SMN1; SMN2TSHRGABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040086949-A1 Method for preparing a ligand presenting assembly (LPA), an LPA and uses thereof STATENS SERUM INSTITUT 2004-05-06 US claimed
EP-1117677-B1 LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF STATENS SERUMINSTITUT (DK) 2003-11-12 EP claimed
EP-3659695-A1 HIGHLY CROSSLINKED HYBRID POLYIMIDE-SILSESQUIOXANE MEMBRANES Universiteit Twente (NL) 2020-06-03 EP disclosed
EP-3041599-B1 HIGHLY CROSSLINKED HYBRID POLYIMIDE-SILSESQUIOXANE MEMBRANES UNIV TWENTE (NL) 2019-10-30 EP disclosed
US-10052592-B2 Highly crosslinked hybrid polyimide-silsesquioxane membranes UNIVERSITEIT TWENTE (NL) 2018-08-21 US disclosed
US-20160199791-A1 HIGHLY CROSSLINKED HYBRID POLYIMIDE-SILSESQUIOXANE MEMBRANES UNIVERSITEIT TWENTE (NL) 2016-07-14 US disclosed
EP-3041599-A1 HIGHLY CROSSLINKED HYBRID POLYIMIDE-SILSESQUIOXANE MEMBRANES Universiteit Twente (NL) 2016-07-13 EP disclosed
EP-2225272-B1 PEPTIDES DERIVED FROM NCAM (FGLS) ENKAM PHARMACEUTICALS AS (DK) 2015-10-21 EP disclosed
US-8470964-B2 Peptides derived from NCAM (FGLs) ENKAM PHARMACEUTICALS A/S (DK) 2013-06-25 US disclosed
EP-1765861-B1 FGFR BINDING PEPTIDES ENKAM PHARMACEUTICALS AS (DK) 2012-02-15 EP disclosed
US-20110098225-A1 NOVEL PEPTIDES DERIVED FROM NCAM (FGLs) COPENHAGEN UNIVERSITY 2011-04-28 US disclosed
EP-1765861-A2 FGFR BINDING PEPTIDES Enkam Pharmaceuticals A/S (DK) 2007-03-28 EP disclosed
EP-1660539-A2 COMPOUNDS COMPRISING LPA Enkam Pharmaceuticals A/S (DK) 2006-05-31 EP disclosed
WO-2005014623-A9 COMPOUNDS COMPRISING LPA 2006-03-23 WO disclosed
WO-2005123759-A2 FGFR BINDING PEPTIDES ENKAM PHARMACEUTICALS A/S (DK) 2005-12-29 WO disclosed
WO-2005121168-A2 HEPARIN BINDING PEPTIDE ENKAM PHARMACEUTICALS A/S (DK) 2005-12-22 WO disclosed
WO-2005014623-A2 COMPOUNDS COMPRISING LPA ENKAM PHARMACEUTICALS A/S (DK) 2005-02-17 WO disclosed
US-20040086949-A1 Method for preparing a ligand presenting assembly (LPA), an LPA and uses thereof STATENS SERUM INSTITUT 2004-05-06 US disclosed
EP-1117677-B1 LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF STATENS SERUMINSTITUT (DK) 2003-11-12 EP disclosed
US-5316860-A Waterproofing leather ROHM AND HAAS COMPANY (US) 1994-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098225-A1 NOVEL PEPTIDES DERIVED FROM NCAM (FGLs) L1CAM, FGFR1, FGFR3 SLC22A6 4392/4885TDP1 3935/4885SMN1; SMN2 465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.