Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898323 | 1.00 | GLO1 (0.64) | GLO1ALDH1A1CYP2D6SMN1; SMN2NPSR1 | |
| SCHEMBL21475435 | 1.00 | GLO1 (0.64) | GLO1ALDH1A1CYP2D6SMN1; SMN2NPSR1 | |
| SCHEMBL26012486 | 0.90 | CYP2D6 (0.62) | GLO1ALDH1A1CYP2D6SMN1; SMN2NPSR1 | |
| SCHEMBL12163006 | 0.85 | GLO1 (0.50) | GLO1ALDH1A1CYP2D6SMN1; SMN2NPSR1 | |
| SCHEMBL24158673 | 0.82 | CYP2D6 (0.50) | GLO1ALDH1A1CYP2D6SMN1; SMN2NPSR1 | |
| SCHEMBL21024972 | 0.79 | CYP2D6 (0.47) | GLO1ALDH1A1CYP2D6SMN1; SMN2NPSR1 | |
| SCHEMBL15884500 | 0.79 | CYP2D6 (0.47) | GLO1ALDH1A1CYP2D6SMN1; SMN2NPSR1 | |
| SCHEMBL15884510 | 0.79 | CYP2D6 (0.47) | GLO1ALDH1A1CYP2D6SMN1; SMN2NPSR1 | |
| SCHEMBL23515594 | 0.79 | GLO1 (0.58) | GLO1ALDH1A1CYP2D6SMN1; SMN2NPSR1 | |
| SCHEMBL8394432 | 0.79 | GLO1 (0.58) | GLO1ALDH1A1CYP2D6SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028507-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-02-03 | — | — | US | disclosed |
| US-20110028507-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028507-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | EGLN3, EGLN2, HIF1A | GLO1 1463/4885ALDH1A1 201/4885CYP2D6 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.