Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435543 | 0.79 | CA12 (0.47) | MAPTALDH1A1KDM4EKMT2ACA12 | |
| SCHEMBL4743617 | 0.75 | CYP1A2 (0.53) | MAPTALDH1A1KDM4EKMT2ACA12 | |
| SCHEMBL3782967 | 0.72 | MMP2 (0.54) | CA12CA9CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL26425567 | 0.71 | CA12 (0.49) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5050954 | 0.71 | CA12 (0.49) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30096658 | 0.71 | CA12 (0.49) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5050905 | 0.71 | CA12 (0.49) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5050904 | 0.71 | CA12 (0.49) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| Benzene SCHEMBL1289719 | 0.71 | MEN1 (0.40) | MAPTALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL27415448 | 0.71 | CYP1A2 (0.49) | MAPTALDH1A1KDM4ECA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046247-A2 | PROCESS FOR THE PREPARATION OF (±M1R(S), 2SRR)L-2-(AMINOMETHYL)-N,N-DIETHYL-L-PHENYLCYCLOPROPANE CARBOXAMIDE HYDROCHLORIDE | MSN LABORATORIES LIMITED (IN) | 2012-04-12 | — | — | WO | claimed |