Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19052367 | 1.00 | LMNA (0.46) | LMNAALDH1A1TDP1USP2MEN1 | |
| SCHEMBL18140052 | 0.91 | LMNA (0.50) | LMNATSHRCA2GPR84FDPS | |
| SCHEMBL10386371 | 0.91 | LMNA (0.50) | LMNATSHRCA2GPR84FDPS | |
| SCHEMBL10385248 | 0.91 | LMNA (0.50) | LMNATSHRCA2GPR84FDPS | |
| SCHEMBL18140609 | 0.91 | LMNA (0.50) | LMNATSHRCA2GPR84FDPS | |
| SCHEMBL18141247 | 0.91 | LMNA (0.50) | LMNATSHRCA2GPR84FDPS | |
| SCHEMBL10385229 | 0.91 | LMNA (0.50) | LMNATSHRCA2GPR84FDPS | |
| SCHEMBL18141381 | 0.91 | LMNA (0.50) | LMNATSHRCA2GPR84FDPS | |
| SCHEMBL18139942 | 0.91 | LMNA (0.50) | LMNATSHRCA2GPR84FDPS | |
| SCHEMBL18139290 | 0.91 | LMNA (0.50) | LMNATSHRCA2GPR84FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8327973-B2 | Foam compositions with enhanced sound attenuation | HEARING COMPONENTS, INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20110031059-A1 | FOAM COMPOSITIONS WITH ENHANCED SOUND ATTENUATION | HEARING COMPONENTS, INC. (US) | 2011-02-10 | — | — | US | disclosed |