Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 17/20 | 0.62 |
| ▸ | CDK9 | P50750 | 4/20 | 0.62 |
| ▸ | CCNK | O75909 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191982 | 0.83 | CCNT1 (0.68) | CCNT1CDK9CCNK | |
| SCHEMBL12850539 | 0.82 | CCNT1 (0.81) | CCNT1CDK9CCNK | |
| SCHEMBL1463086 | 0.81 | CCNT1 (0.66) | CCNT1CDK9CCNK | |
| SCHEMBL16588554 | 0.81 | CCNT1 (0.66) | CCNT1CDK9CCNK | |
| SCHEMBL12826909 | 0.78 | CCNT1 (0.71) | CCNT1CDK9CCNK | |
| SCHEMBL1947114 | 0.77 | CDK9 (1.00) | CCNT1CDK9 | |
| SCHEMBL12565538 | 0.77 | CDK9 (1.00) | CCNT1CDK9 | |
| SCHEMBL1946295 | 0.77 | CDK9 (1.00) | CCNT1CDK9 | |
| SCHEMBL1192233 | 0.76 | CDK9 (0.66) | CCNT1CDK9CCNK | |
| SCHEMBL12565541 | 0.76 | CCNT1 (0.75) | CCNT1CDK9CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012661-A1 | PYRIDINE AND PYRAZINE DERIVATIVES AS PROTEIN KINASE MODULATORS | NOVARTIS AG (CH) | 2011-02-03 | — | — | WO | disclosed |