Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 4/20 | 0.46 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486754 | 0.83 | CA12 (0.37) | GRIA4 | |
| SCHEMBL12898957 | 0.79 | GRIA4 (0.47) | GRIA4 | |
| SCHEMBL12884417 | 0.79 | GRIA4 (0.44) | GRIA4PER2CRY1CRY2 | |
| SCHEMBL12203090 | 0.78 | GRIA4 (0.43) | GRIA4PER2CRY1CRY2 | |
| SCHEMBL17885764 | 0.77 | GRIA4 (0.36) | GRIA4ALDH1A1 | |
| SCHEMBL22457461 | 0.75 | GRIA4 (0.40) | GRIA4PER2CRY1CRY2ALDH1A1 | |
| SCHEMBL16611402 | 0.75 | — | — | |
| SCHEMBL4119947 | 0.74 | GRIA4 (0.41) | GRIA4PER2CRY1CRY2 | |
| SCHEMBL4119954 | 0.74 | GRIA4 (0.41) | GRIA4PER2CRY1CRY2 | |
| SCHEMBL91255 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028447-A1 | INDAZOLE DERIVATIVES | PFIZER INC. | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028447-A1 | INDAZOLE DERIVATIVES | CNR1, CNR2, GPR119 | GRIA4 566/4885PER2 1302/4885CRY1 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.