Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9914035 | 0.98 | FUCA1 (0.54) | FUCA1GLASMN1; SMN2CA9CA2 | |
| SCHEMBL9914008 | 0.98 | FUCA1 (0.54) | FUCA1GLASMN1; SMN2CA9CA2 | |
| SCHEMBL14025399 | 0.98 | FUCA1 (0.54) | FUCA1GLASMN1; SMN2CA9CA2 | |
| SCHEMBL15978525 | 0.86 | FUCA1 (0.40) | FUCA1GLACA9CA2CA1 | |
| SCHEMBL20786630 | 0.81 | GLA (0.49) | GLA | |
| SCHEMBL13951673 | 0.81 | GLA (0.41) | FUCA1GLA | |
| SCHEMBL30483914 | 0.79 | PYGB (0.47) | GLA | |
| SCHEMBL9235423 | 0.79 | PYGB (0.47) | GLA | |
| SCHEMBL17174983 | 0.78 | FUCA1 (0.38) | FUCA1GLA | |
| SCHEMBL9915177 | 0.78 | FUCA1 (0.41) | FUCA1GLACA9CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884202-B2 | Nucleobases are perfluoroalkylated in a one step process with a perfluoroalkyl halide in the presence of a sulfoxide, a peroxide and an iron compound; useful as medicinal drugs, intermediates for medicinal drugs and agricultural chemicals | TOSOH CORPORATION (JP) | 2011-02-08 | — | — | US | disclosed |