SCHEMBL12900985

SCHEMBL12900985

COC(=O)CC(C)(C)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18903926 0.81 TSHR (0.39)
SCHEMBL13059617 0.80 TSHR (0.37)
Formaldehyde SCHEMBL3824097 0.79 TSHR (0.46)
SCHEMBL8903958 0.79
SCHEMBL167149 0.78
SCHEMBL667630 0.78 TSHR (0.50)
SCHEMBL10717198 0.77
Ammonia Solution, Strong SCHEMBL3909004 0.76 TSHR (0.48)
SCHEMBL585604 0.76
SCHEMBL7047649 0.76 HMGCR (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024034583-A1 METHOD FOR PRODUCING HALOGENATED ALKENE COMPOUND ダイキン工業株式会社 2024-02-15 WO disclosed
EP-2268140-B1 NOVEL COMPOUNDS ADVANTAGEOUS IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS AURIMMED PHARMA INC (US) 2020-11-11 EP disclosed
US-20160137592-A1 NOVEL COMPOUNDS ADVANTAGEOUS IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS AURIMMED PHARMA, INC. 2016-05-19 US disclosed
US-9212155-B2 Compounds advantageous in the treatment of central nervous system diseases and disorders AURIMMED PHARMA, INC. (US) 2015-12-15 US disclosed
US-9206143-B2 Compounds advantageous in the treatment of central nervous system diseases and disorders AURIMMED PHARMA, INC. (US) 2015-12-08 US disclosed
US-20110046138-A1 NOVEL COMPOUNDS ADVANTAGEOUS IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS AURIMMED PHARMA, INC. 2011-02-24 US disclosed
CN-1660766-A Ramification of omega oxyacid with lateral chain of chirality methyl SHANGHAI INST ORGANIC CHEM (CN) 2005-08-31 CN disclosed