Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12901055 | 0.80 | APP (0.30) | APPMAPT | |
| SCHEMBL2057383 | 0.78 | TDP1 (0.32) | LMNAHTTALDH1A1MAPT | |
| SCHEMBL12901031 | 0.71 | — | — | |
| SCHEMBL12901132 | 0.71 | KMT2A (0.47) | ALDH1A1TSHRMAPT | |
| SCHEMBL3557265 | 0.62 | PDK2 (0.41) | TTRALDH1A1TSHRCYP2A6 | |
| SCHEMBL17515239 | 0.62 | MLNR (0.38) | TTRALDH1A1TSHRCYP2A6 | |
| SCHEMBL12934281 | 0.58 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP2A6 | |
| SCHEMBL29588873 | 0.58 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP2A6 | |
| SCHEMBL15118514 | 0.56 | ALDH1A1 (0.33) | LMNAHTTALDH1A1CYP2A6 | |
| SCHEMBL5846694 | 0.55 | ALDH1A1 (0.41) | LMNATTRALDH1A1TSHRCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835632-B2 | Methods to increase the photostability of dyes | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-09-16 | — | — | US | disclosed |
| US-20110046000-A1 | METHODS TO INCREASE THE PHOTOSTABILITY OF DYES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-02-24 | — | — | US | disclosed |
| WO-2008157762-A2 | METHODS TO INCREASE THE PHOTOSTABILITY OF DYES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046000-A1 | METHODS TO INCREASE THE PHOTOSTABILITY OF DYES | PTMS, ACP1, SNRPE | LMNA 1662/4885HTT 3252/4885TTR 1492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.